Shortening the decade‐long gap between adult and paediatric drug formulations: a new framework based on the HIV experience in low‐ and middle‐income countries
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25049
Abstract: Despite the coordinated efforts by several stakeholders to speed up access to HIV treatment for children, development of optimal paediatric formulations still lags 8 to 10 years behind that of adults, due mainly to lack… read more here.
Keywords: paediatric drug; shortening decade; drug formulations; decade long ... See more keywords
Pharmaceutical challenges and perspectives in developing ophthalmic drug formulations
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-018-0404-6
Abstract: Ocular drug delivery has been widely recognized as an attractive route for drug administration for cures of ocular diseases. Overall, designing an effective therapy to cure ocular diseases has been considered as a formidable task.… read more here.
Keywords: drug delivery; drug; drug formulations; ocular drug ... See more keywords
3D printing of gummy drug formulations composed of gelatin and an HPMC-based hydrogel for pediatric use.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120118
Abstract: The 3D printing of drug formulations is a promising method for preparing tailored medicines following the approval of 3D printed tablets by the US FDA in 2015. Appropriate dosage forms for pediatric patients are deficient… read more here.
Keywords: drug; drug formulations; gelatin hpmc; gummy drug ... See more keywords
Drug delivery to the anterior segment of the eye: a review of current and future treatment strategies.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120924
Abstract: Research in the development of ophthalmic drug formulations and innovative technologies over the past few decades has been directed at improving the penetration of medications delivered to the eye. Currently, approximately 90% of all ophthalmic… read more here.
Keywords: drug delivery; drug; drug formulations; delivery anterior ... See more keywords
Modified electrodes for electrochemical determination of metronidazole in drug formulations and biological samples: An overview
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106151
Abstract: Abstract Metronidazole (MTZ) is an antibiotic drug derived from nitroimidazole, widely utilized for the treatment of various diseases caused by anaerobic bacteria and protozoa in human and domestic animal. However, this medicine is banned in… read more here.
Keywords: drug; drug formulations; modified electrodes; electrochemical determination ... See more keywords
Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations.
Sign Up to like & getrecommendations! Published in 2020 at "Science advances"
DOI: 10.1126/sciadv.abb6594
Abstract: Inefficient injection of microparticles through conventional hypodermic needles can impose serious challenges on clinical translation of biopharmaceutical drugs and microparticle-based drug formulations. This study aims to determine the important factors affecting microparticle injectability and establish… read more here.
Keywords: microparticle based; framework; drug formulations; microparticle ... See more keywords
Impact of Liposomal Drug Formulations on the RBCs Shape, Transmembrane Potential, and Mechanical Properties
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DOI: 10.3390/ijms22041710
Abstract: Liposomal technologies are used in order to improve the effectiveness of current therapies or to reduce their negative side effects. However, the liposome–erythrocyte interaction during the intravenous administration of liposomal drug formulations may result in… read more here.
Keywords: transmembrane potential; formulations rbcs; drug; drug formulations ... See more keywords
Enhanced NSAIDs Solubility in Drug–Drug Formulations with Ciprofloxacin
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043305
Abstract: Drug–drug salts are a kind of pharmaceutical multicomponent solid in which the two co-existing components are active pharmaceutical ingredients (APIs) in their ionized forms. This novel approach has attracted great interest in the pharmaceutical industry… read more here.
Keywords: drug formulations; nsaids solubility; enhanced nsaids; drug drug ... See more keywords
Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13030389
Abstract: Co-amorphous drug delivery systems (CAMS) are characterized by the combination of two or more (initially crystalline) low molecular weight components that form a homogeneous single-phase amorphous system. Over the past decades, CAMS have been widely… read more here.
Keywords: drug; drug formulations; amorphous drug; performance ... See more keywords
Recent Advances in Biocompatible Ionic Liquids in Drug Formulation and Delivery
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15041179
Abstract: The development of effective drug formulations and delivery systems for newly developed or marketed drug molecules remains a significant challenge. These drugs can exhibit polymorphic conversion, poor bioavailability, and systemic toxicity, and can be difficult… read more here.
Keywords: drug formulations; delivery systems; ionic liquids; formulations delivery ... See more keywords