DAMPs and sterile inflammation in drug hepatotoxicity
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology International"
DOI: 10.1007/s12072-018-9911-9
Abstract: Drug hepatotoxicity is the leading cause of acute liver failure (ALF) in the developed countries. The early diagnosis and treatment are still problematic, and one important reason is the lack of reliable mechanistic biomarkers and… read more here.
Keywords: phase; drug hepatotoxicity; acetaminophen; sterile inflammation ... See more keywords
The assessment of the potential hepatotoxicity of new drugs by in vitro metabolomics
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1155271
Abstract: Drug hepatotoxicity assessment is a relevant issue both in the course of drug development as well as in the post marketing phase. The use of human relevant in vitro models in combination with powerful analytical… read more here.
Keywords: drug hepatotoxicity; potential hepatotoxicity; assessment potential; hepatotoxicity ... See more keywords