Drug Holiday in Metastatic Renal‐Cell Carcinoma Patients Treated With Vascular Endothelial Growth Factor Receptor Inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2017.12.014
Abstract: &NA; Treatment of metastatic renal‐cell carcinoma (mRCC) may be associated with significant toxicities necessitating drug holidays. Outcomes of 112 patients who underwent drug holidays were analyzed. Complete response before the initial drug holiday was associated… read more here.
Keywords: drug holiday; renal cell; drug; drug holidays ... See more keywords
Efficacy of a high-dose antiresorptive drug holiday to reduce the risk of medication-related osteonecrosis of the jaw (MRONJ): A systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e03795
Abstract: A temporary discontinuation (drug holiday) of high-dose antiresorptive (AR) agents has been proposed to reduce the risk of medication-related osteonecrosis of the jaw (MRONJ). The aim of this systematic review was to answer the question:… read more here.
Keywords: dose antiresorptive; drug holiday; mronj; high dose ... See more keywords
Maintenance therapy and drug holiday in sarcoma patients: systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Acta Oncologica"
DOI: 10.1080/0284186x.2020.1759825
Abstract: Abstract Purpose: Overall prognosis of advanced sarcoma remains poor, optimization of systemic treatment is urgently needed in this setting. Materials and methods: We systematically reviewed fully published English-speaking literature about maintenance therapy and drug holiday… read more here.
Keywords: maintenance therapy; sarcoma; maintenance; drug holiday ... See more keywords
Long‐term efficacy of a Vismodegib regime including a 1‐week drug holiday every month in two patients with Gorlin Goltz syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Dermatologic Therapy"
DOI: 10.1111/dth.15293
Abstract: Dear Editor, Gorlin Goltz syndrome (GGS), also known as Nevoid basal cell carcinoma syndrome, is a rare, autosomal dominant multisystemic disorder with an estimated prevalence of, on average, 1 in 100,000 people. This condition is… read more here.
Keywords: drug; drug holiday; treatment; year ... See more keywords
OP0017 The impact of the duration of bisphosphonate drug holidays on hip fracture rates
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.4953
Abstract: Background Given FDA warnings, drug holidays (temporary or permanent discontinuation) of bisphosphonates (BPs) after long-term (3–5 years) continuous therapy is becoming increasingly common in the United States (US). However, the benefits and risks of stopping… read more here.
Keywords: drug holiday; fracture; drug; hip fracture ... See more keywords
Skeletal outcomes of patients with osteogenesis imperfecta during drug holiday of bisphosphonates: a real-world study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.901925
Abstract: Purpose This study aimed to investigate the skeletal outcomes of patients with osteogenesis imperfecta (OI) who received bisphosphonate (BP) treatment and entered drug holiday after achieving an age- and sex-specific bone mineral density (BMD) reference.… read more here.
Keywords: drug holidays; drug holiday; treatment; drug ... See more keywords
To repeat or not to repeat? Measuring bone mineral density during anti-resorptive therapy or a drug holiday
Sign Up to like & getrecommendations! Published in 2023 at "Cleveland Clinic Journal of Medicine"
DOI: 10.3949/ccjm.90a.22071
Abstract: An initial bone mineral density (BMD) measurement is used to diagnose osteoporosis and decide whether patients need treatment, but the utility of repeating this test in those on treatment or on a drug holiday (ie,… read more here.
Keywords: bone mineral; mineral density; repeat; drug holiday ... See more keywords