Plasma Protein-Mediated Uptake and Contradictions to the Free Drug Hypothesis: A Critical Review.
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DOI: 10.1080/03602532.2023.2195133
Abstract: According to the free drug hypothesis (FDH), only free, unbound drug is available to interact with biological targets. This hypothesis is the fundamental principle that continues to explain the vast majority of all pharmacokinetic and… read more here.
Keywords: plasma protein; protein mediated; drug hypothesis; mediated uptake ... See more keywords