Articles with "drug indications" as a keyword



FDA Approval of Orphan Drug Indications for Pediatric Patients, 2011-2023

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Published in 2024 at "JAMA Pediatrics"

DOI: 10.1001/jamapediatrics.2024.5280

Abstract: This cohort study assesses Pediatric Research Equity Act amendments that may influence approval of orphan drug indications for pediatric patients under current regulatory programs. read more here.

Keywords: approval orphan; pediatric patients; indications pediatric; drug indications ... See more keywords

Formalizing drug indications on the road to therapeutic intent

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Published in 2017 at "Journal of the American Medical Informatics Association : JAMIA"

DOI: 10.1093/jamia/ocx064

Abstract: Abstract Therapeutic intent, the reason behind the choice of a therapy and the context in which a given approach should be used, is an important aspect of medical practice. There are unmet needs with respect… read more here.

Keywords: therapeutic intent; formalizing drug; drug indications; intent ... See more keywords

Comparing the Approval and Coverage Decisions of New Oncology Drugs in the United States and Other Selected Countries.

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Published in 2017 at "Journal of managed care & specialty pharmacy"

DOI: 10.18553/jmcp.2017.23.2.247

Abstract: BACKGROUND Global pharmaceutical sales for anticancer drugs were $74.4 billion in 2014, ranking first for drugs by therapeutic class. Countries may differ substantially in the approval and coverage decisions for anticancer drugs. OBJECTIVE To compare… read more here.

Keywords: coverage decisions; drug indications; oncology; approval coverage ... See more keywords

Combining biomedical knowledge graphs and text to improve predictions for drug-target interactions and drug-indications

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Published in 2022 at "PeerJ"

DOI: 10.7717/peerj.13061

Abstract: Biomedical knowledge is represented in structured databases and published in biomedical literature, and different computational approaches have been developed to exploit each type of information in predictive models. However, the information in structured databases and… read more here.

Keywords: information; biomedical knowledge; knowledge; drug indications ... See more keywords