5 Clinical Evaluation of the Abuse Potential of Buprenorphine/Samidorphan Combination
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DOI: 10.1017/s1092852919000038
Abstract: Abstract Introduction Buprenorphine (BUP)/samidorphan (SAM) combination is an opioid system modulator being investigated as an adjunctive treatment for major depressive disorder (MDD). BUP/SAM is a fixed-dose combination of BUP, a partial ยต-opioid receptor agonist and… read more here.
Keywords: bup; combination; drug liking; abuse potential ... See more keywords
10 Pharmacodynamics and Tolerability of Intranasally Administered Immediate-Release Amphetamine Sulfate Among Recreational Intranasal StimulantUsers
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DOI: 10.1017/s1092852919000063
Abstract: Abstract Study Objective Despite increased nonmedical use of ADHD prescription stimulants, there are limited data to inform selection of intranasal doses for abuse-potential evaluations. This study determined a dose of amphetamine sulfate that is tolerable… read more here.
Keywords: intranasal; amphetamine sulfate; drug liking; placebo ... See more keywords
How High Can Patients Get on CBD?
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DOI: 10.1177/1535759719874408
Abstract: Abuse potential assessment of cannabidiol (CBD) in recreational polydrug users: A randomized, double-blind, controlled trial Schoedel KA, Szeto I, Setnik B, et al. Epilepsy Behav. 2018;88:162-171. doi:10.1016/j.yebeh.2018.07.027. Epub October 2, 2018. PMID: 30286443. Rationale: Treatment… read more here.
Keywords: drug liking; cbd; drug; adverse events ... See more keywords