Molecularly engineering a dual-drug nanoassembly for self-sensitized photodynamic therapy via thioredoxin impairment and glutathione depletion
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DOI: 10.1080/10717544.2022.2141920
Abstract: Abstract Photodynamic therapy (PDT) has been extensively investigated as a spatiotemporally noninvasive and controllable modality for cancer treatment. However, the intracellular antioxidant systems mainly consisting of thioredoxin (Trx) and glutathione (GSH) significantly counteract and prevent… read more here.
Keywords: antioxidant systems; photodynamic therapy; dual drug; drug nanoassembly ... See more keywords