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Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12619
Abstract: Acetazolamide is an old drug used as an antiepileptic agent, amongst other indications. The drug is seldom used, primarily due to perceived poor efficacy and adverse events. Acetazolamide acts as a noncompetitive inhibitor of carbonic…
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Keywords:
drug new;
acetazolamide old;
evidence;
new evidence ... See more keywords
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Published in 2017 at "Journal of cardiothoracic and vascular anesthesia"
DOI: 10.1053/j.jvca.2016.03.134
Abstract: From the Lynn Heart and Vascular Institute, Boca Raton Regional Hospital, and Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL. Address reprint requests to Alexander Kulik, MD, MPH, Lynn Heart and…
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Keywords:
old drug;
systematic review;
drug new;
boca raton ... See more keywords
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Published in 2020 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13392
Abstract: Paracetamol (acetaminophen) is the most commonly used over‐the‐counter (OTC) drug in the world. Despite its popularity and use for many years, the safety of its application and its mechanism of action are still unclear. Currently,…
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Keywords:
old drug;
new mechanisms;
drug new;
paracetamol old ... See more keywords
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Published in 2020 at "Hip International"
DOI: 10.17863/cam.37824
Abstract: Introduction:Neck of femur fractures are common in the comorbid, often anticoagulated, elderly. Non-vitamin K antagonist oral anticoagulants (NOACs) may affect patient outcomes. We aimed to evaluat...
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Keywords:
new problem;
problem hip;
drug new;
hip ... See more keywords
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Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666170330091438
Abstract: BACKGROUND Research into gold-based drugs for a range of human diseases has seen a revival in recent years. This article reviews the most important applications of gold products in different fields of human pathology. Au(I)…
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Keywords:
gold old;
medicine;
old drug;
drug new ... See more keywords
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Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10050756
Abstract: Spironolactone (SP) is commonly used for the treatment of heart failure, hypertension, and complications of cirrhosis by antagonizing the mineralocorticoid receptor. However, SP also antagonizes the androgen receptor, and thus SP has also been shown…
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Keywords:
xpb;
xpb old;
old drug;
drug new ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084167
Abstract: Theophylline (3-methyxanthine) is a historically prominent drug used to treat respiratory diseases, alone or in combination with other drugs. The rapid onset of the COVID-19 pandemic urged the development of effective pharmacological treatments to directly…
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Keywords:
drug new;
theophylline old;
pharmacology;
drug ... See more keywords
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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28083624
Abstract: Cancer metabolic plasticity, including changes in fatty acid metabolism utilisation, is now widely appreciated as a key driver for cancer cell growth, survival and malignancy. Hence, cancer metabolic pathways have been the focus of much…
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Keywords:
drug new;
perhexiline old;
anti cancer;
cancer ... See more keywords