Articles with "drug new" as a keyword



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Acetazolamide: Old drug, new evidence?

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Published in 2022 at "Epilepsia Open"

DOI: 10.1002/epi4.12619

Abstract: Acetazolamide is an old drug used as an antiepileptic agent, amongst other indications. The drug is seldom used, primarily due to perceived poor efficacy and adverse events. Acetazolamide acts as a noncompetitive inhibitor of carbonic… read more here.

Keywords: drug new; acetazolamide old; evidence; new evidence ... See more keywords
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Old Drug, New Route: A Systematic Review of Intravenous Acetaminophen After Adult Cardiac Surgery.

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Published in 2017 at "Journal of cardiothoracic and vascular anesthesia"

DOI: 10.1053/j.jvca.2016.03.134

Abstract: From the Lynn Heart and Vascular Institute, Boca Raton Regional Hospital, and Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL. Address reprint requests to Alexander Kulik, MD, MPH, Lynn Heart and… read more here.

Keywords: old drug; systematic review; drug new; boca raton ... See more keywords
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Paracetamol – An old drug with new mechanisms of action

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Published in 2020 at "Clinical and Experimental Pharmacology and Physiology"

DOI: 10.1111/1440-1681.13392

Abstract: Paracetamol (acetaminophen) is the most commonly used over‐the‐counter (OTC) drug in the world. Despite its popularity and use for many years, the safety of its application and its mechanism of action are still unclear. Currently,… read more here.

Keywords: old drug; new mechanisms; drug new; paracetamol old ... See more keywords

New drug, new problem: do hip fracture patients taking NOACs experience delayed surgery, longer hospital stay, or poorer outcomes?

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Published in 2020 at "Hip International"

DOI: 10.17863/cam.37824

Abstract: Introduction:Neck of femur fractures are common in the comorbid, often anticoagulated, elderly. Non-vitamin K antagonist oral anticoagulants (NOACs) may affect patient outcomes. We aimed to evaluat... read more here.

Keywords: new problem; problem hip; drug new; hip ... See more keywords
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Gold - Old Drug with New Potentials.

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Published in 2018 at "Current medicinal chemistry"

DOI: 10.2174/0929867324666170330091438

Abstract: BACKGROUND Research into gold-based drugs for a range of human diseases has seen a revival in recent years. This article reviews the most important applications of gold products in different fields of human pathology. Au(I)… read more here.

Keywords: gold old; medicine; old drug; drug new ... See more keywords
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Spironolactone and XPB: An Old Drug with a New Molecular Target

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Published in 2020 at "Biomolecules"

DOI: 10.3390/biom10050756

Abstract: Spironolactone (SP) is commonly used for the treatment of heart failure, hypertension, and complications of cirrhosis by antagonizing the mineralocorticoid receptor. However, SP also antagonizes the androgen receptor, and thus SP has also been shown… read more here.

Keywords: xpb; xpb old; old drug; drug new ... See more keywords
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Theophylline: Old Drug in a New Light, Application in COVID-19 through Computational Studies

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23084167

Abstract: Theophylline (3-methyxanthine) is a historically prominent drug used to treat respiratory diseases, alone or in combination with other drugs. The rapid onset of the COVID-19 pandemic urged the development of effective pharmacological treatments to directly… read more here.

Keywords: drug new; theophylline old; pharmacology; drug ... See more keywords
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Perhexiline: Old Drug, New Tricks? A Summary of Its Anti-Cancer Effects

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28083624

Abstract: Cancer metabolic plasticity, including changes in fatty acid metabolism utilisation, is now widely appreciated as a key driver for cancer cell growth, survival and malignancy. Hence, cancer metabolic pathways have been the focus of much… read more here.

Keywords: drug new; perhexiline old; anti cancer; cancer ... See more keywords