Molecular mechanism of QH-BJ drug pair in the treatment of systemic lupus erythematosus based on network pharmacology and molecular docking
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DOI: 10.1097/md.0000000000032062
Abstract: To analyze the molecular mechanism of Qinghao-Biejia (QH-BJ) drug pair in the treatment of systemic lupus erythematosus (SLE) based on the method of network pharmacology and molecular docking technology. The components and related targets of… read more here.
Keywords: pharmacology; drug pair; pair treatment;
Eucommia ulmoides Oliver-Tribulus terrestris L. Drug Pair Regulates Ferroptosis by Mediating the Neurovascular-Related Ligand-Receptor Interaction Pathway- A Potential Drug Pair for Treatment Hypertension and Prevention Ischemic Stroke
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DOI: 10.3389/fneur.2022.833922
Abstract: Background In this study, we used the network pharmacology approach to explore the potential disease targets of the Eucommia ulmoides Oliver (EUO)-Tribulus terrestris L. (TT) drug pair in the treatment of hypertension-associated neurovascular lesions and… read more here.
Keywords: ligand receptor; drug pair; receptor interaction; drug ... See more keywords
Astragalus–Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy
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DOI: 10.3389/fphar.2022.895696
Abstract: Objective: Prostate cancer (PCa) is an epithelial malignancy of the prostate that currently lacks effective treatment. Traditional Chinese medicine (TCM) can play an anticancer role through regulating the immune system, anti-tumor angiogenesis, regulating tumor cell… read more here.
Keywords: akt mtor; drug pair; pi3k akt; drug ... See more keywords
Qualitative and quantitative analysis of the bioactive components of “ginseng–polygala” drug pair against PC12 cell injury based on UHPLC-QTOF-MS and HPLC
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DOI: 10.3389/fphar.2022.949757
Abstract: Aβ25-35-induced PC12 cells were used as the in vitro injury model to evaluate the effects on PC12 cells after intervention with the “ginseng–polygala” drug pair. The results showed that the drug pair could significantly increase… read more here.
Keywords: drug pair; bioactive components; polygala drug; ginseng polygala ... See more keywords
Study on the mechanism of Danshen-Guizhi drug pair in the treatment of ovarian cancer based on network pharmacology and in vitro experiment
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DOI: 10.7717/peerj.13148
Abstract: Our study aims to explore the active components and mechanisms of the Danshen-Guizhi drug pair in treating ovarian cancer by network pharmacology and in vitro experiment. The “component-target-pathway” diagram of the Danshen-Guizhi drug pair was… read more here.
Keywords: pharmacology; drug pair; guizhi drug; danshen guizhi ... See more keywords