DNA framework carriers with asymmetric hydrophobic drug patterns for enhanced cellular cytotoxicity.
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DOI: 10.1039/d2cc05763h
Abstract: We devise a class of amphiphilic drug complexes by programming hydrophobic drug patterns (HDPs) on DNA frameworks. We investigate the effect of HDPs on cellular uptake efficiency and drug potency. We achieve enhanced cytotoxicity against… read more here.
Keywords: cytotoxicity; drug patterns; dna framework; framework carriers ... See more keywords