Mechanical properties and drug permeability of the PA6 membranes prepared by immersion precipitation from PA6 - formic acid - water system
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Membrane Science"
DOI: 10.1016/j.memsci.2018.05.022
Abstract: Abstract The paper presents the effect of polymer solution composition on the morphology, mechanical properties and drug permeability of the asymmetric polyamide 6 (PA6) membranes prepared by immersion precipitation. The effect of polymer solution composition… read more here.
Keywords: drug permeability; formic acid; drug; permeability ... See more keywords
Atorvastatin Potentially Reduces Mycobacterial Severity through Its Action on Lipoarabinomannan and Drug Permeability in Granulomas
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03197-22
Abstract: Mycobacterium tuberculosis binds to and enters the macrophage via the cell membrane cholesterol. M. tuberculosis limits phagosomal maturation and activation without engaging in phagocytosis. Aggregation of cholesterol in the cell wall of M. tuberculosis and… read more here.
Keywords: cell; tuberculosis; drug permeability; cholesterol ... See more keywords
An Evaluation of the Drug Permeability Properties of Human Cadaveric In Situ Tympanic and Round Window Membranes
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15091037
Abstract: It is estimated that hearing loss currently affects more than 1.5 billion people, or approximately 20% of the global population; however, presently, there are no Food and Drug Administration-approved therapeutics or prophylactics for this condition.… read more here.
Keywords: window membranes; permeability properties; drug permeability; round window ... See more keywords
An In Vitro Model for Characterization of Drug Permeability across the Tympanic Membrane
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15091114
Abstract: Otic disorders, such as otitis media and hearing loss, affect a substantial portion of the global population. Despite this, oto-therapeutics, in particular those intended to treat hearing loss, have seen limited development and innovation. A… read more here.
Keywords: drug permeability; permeability across; vitro model; permeability ... See more keywords
Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12030242
Abstract: Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using the rat single-pass intestinal perfusion model. This… read more here.
Keywords: permeation enhancers; regional intestinal; drug permeability; permeability ... See more keywords
Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa via an In Vitro Model
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14091938
Abstract: Modulation of drug transporter activity at mucosal sites of HIV-1 transmission may be exploited to optimize retention of therapeutic antiretroviral drug concentrations at target submucosal CD4+ T cells. Previously, we showed that darunavir was a… read more here.
Keywords: transporter; drug permeability; model; antiretroviral drug ... See more keywords