FL-DTD: an integrated pipeline to predict the drug interacting targets by feedback loop-based network analysis
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac263
Abstract: Drug target discovery is an essential step to reveal the mechanism of action (MoA) underlying drug therapeutic effects and/or side effects. Most of the approaches are usually labor-intensive while unable to identify the tissue-specific interacting… read more here.
Keywords: integrated pipeline; interacting targets; predict drug; drug perturbation ... See more keywords
Screening Potential Drugs for the Development of NAFLD Based on Drug Perturbation Gene Set
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/7606716
Abstract: Nonalcoholic fatty liver disease (NAFLD) has become one of the problems affecting the health of the population worldwide. The progressive disease includes nonalcoholic steatohepatitis (NASH) and fibrosis, which with no approved therapy, system identification of… read more here.
Keywords: perturbation gene; drugs development; drug perturbation; gene set ... See more keywords