Estimated Costs of Severe Adverse Drug Reactions Resulting in Hospitalization in the Veterans Health Administration
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DOI: 10.1001/jamanetworkopen.2021.47909
Abstract: This quality improvement study uses Veterans Health Administration (VHA) data to estimate the costs of severe adverse drug reactions resulting in or contributing to hospitalizations. read more here.
Keywords: drug reactions; veterans health; severe adverse; costs severe ... See more keywords
Sex Differences in Reported Adverse Drug Reactions to Angiotensin-Converting Enzyme Inhibitors
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DOI: 10.1001/jamanetworkopen.2022.8224
Abstract: This cross-sectional study investigates differences by sex in reporting of adverse drug reactions associated with angiotensin-converting enzyme inhibitors combining global and prescription-corrected databases. read more here.
Keywords: drug reactions; converting enzyme; enzyme inhibitors; sex ... See more keywords
Incidence of Adverse Drug Reactions in COVID‐19 Patients in China: An Active Monitoring Study by Hospital Pharmacovigilance System
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1866
Abstract: To evaluate the incidence, type, and risk factors associated with adverse drug reactions (ADRs) among patients with coronavirus disease 2019 (COVID‐19) by Hospital Pharmacovigilance System (CHPS). A retrospective analysis was performed on 217 patients with… read more here.
Keywords: system; drug reactions; active monitoring; hospital ... See more keywords
A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ma1219-210rr
Abstract: Recently a G‐protein‐coupled receptor, MAS Related GPR Family Member X2 (MRGPRX2), was identified as a specific receptor on human mast cells responsible for IgE independent adverse drug reactions (ADR). Although a murine homologue, Mrgprb2, has… read more here.
Keywords: mice; mcs; human mcs; mast cells ... See more keywords
Metabolovigilance: Associating Drug Metabolites with Adverse Drug Reactions
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DOI: 10.1002/minf.202100261
Abstract: The Metabolovigilance database (https://pharmacogenomics.clas.ucdenver.edu/pharmacogenomics/side‐effect/) is a single repository of information on over 15,920 pharmaceuticals and the compounds expected to result from metabolism of these drugs. Metabolovigilance functions as both a web server, providing data directly… read more here.
Keywords: drug reactions; information; adverse drug; metabolovigilance associating ... See more keywords
Are non‐allergic drug reactions commonly documented as medication “allergies”? A national cohort of Veterans' admissions from 2000 to 2014
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4134
Abstract: Adverse drug reactions (ADRs) including medication allergies are not well‐described among large national cohorts. This study described the most common documented medication allergies and their reactions among a national cohort of Veterans Affairs (VA) inpatients. read more here.
Keywords: medication allergies; drug reactions; drug; documented medication ... See more keywords
Time to onset in statistical signal detection revisited: A follow‐up study in long‐term onset adverse drug reactions
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4790
Abstract: In a previous study, we developed a signal detection method using the time to onset (TTO) of adverse drug reactions (ADRs). The aim of the current study was to investigate this method in a subset… read more here.
Keywords: drug reactions; study; drug; signal detection ... See more keywords
Predictors of adverse drug reactions associated with ribavirin in direct‐acting antiviral therapies for chronic hepatitis C
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DOI: 10.1002/pds.4904
Abstract: To identify factors associated with the development of adverse drug reactions (ADR) in ribavirin therapeutic regimens. read more here.
Keywords: predictors adverse; drug reactions; associated ribavirin; drug ... See more keywords
A retrospective analysis of reporting of adverse drug reactions over 4 years in a primary care health clinic in Malaysia
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DOI: 10.1002/pds.4913
Abstract: Letter to the editor We respectfully take issue with the recent article published in the journal by Hughes and Weiss which offers a valuable and thoughtful documentation of various barriers and potential facilitators to reporting… read more here.
Keywords: drug reactions; malaysia; primary care; drug ... See more keywords
Incidence and outcomes of adverse drug reactions to first‐line anti‐tuberculosis drugs and their effects on the quality of life: A multicenter prospective cohort study
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DOI: 10.1002/pds.5513
Abstract: In tuberculosis (TB) treatment, adverse drug reactions (ADRs) can interrupt treatment and decrease the quality of life (QoL). We aimed to prospectively investigate the incidence of ADRs to first‐line anti‐TB drugs and related outcomes and… read more here.
Keywords: drug reactions; first line; adverse drug; drug ... See more keywords
The Immunogenetics of Cutaneous Drug Reactions.
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DOI: 10.1007/978-3-030-92616-8_17
Abstract: Adverse drug reactions (ADRs) are the cause of nearly three to six percent of inpatient admissions and are associated with high morbidity and mortality rates. Cutaneous adverse drug reactions (cADRs) represent the most frequent ADRs… read more here.
Keywords: drug reactions; cutaneous drug; drug; immunogenetics cutaneous ... See more keywords