Comparing non-occupational post-exposure prophylaxis drug regimens for HIV: insights from a linked HIV surveillance system.
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DOI: 10.1071/sh16132
Abstract: Background International non-occupational post-exposure prophylaxis (NPEP) guidelines recommend routine use of three drug NPEP regimens, despite absence of evidence for greater prevention efficacy compared with two drug regimens. This study examines the potential for excess… read more here.
Keywords: drug npep; drug regimens; exposure prophylaxis; three drug ... See more keywords
Risks and benefits of reducing the number of drugs to treat HIV-1 infection
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2021.1887135
Abstract: ABSTRACT Introduction: Despite the efficacy and safety of antiretroviral therapy, new treatment options are needed to address the concerns of patients and physicians regarding long-term toxicities, costs, and convenience of lifelong antiretroviral therapy. To achieve… read more here.
Keywords: drug regimens; two drug; safety; drug ... See more keywords
Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma
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DOI: 10.1080/2162402x.2021.1992880
Abstract: ABSTRACT Targeted and immunotherapy regimens have revolutionized the treatment of advanced melanoma patients. Despite this, only a subset of patients respond durably. Recently, combination strategies of BRAF/MEK inhibitors with immune checkpoint inhibitor monotherapy (α-CTLA-4 or… read more here.
Keywords: immunotherapy; treatment; braf mek; multi drug ... See more keywords
Real world use of dolutegravir two drug regimens
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DOI: 10.1097/qad.0000000000003480
Abstract: Background: Since 2015, we prescribed dolutegravir (DTG)-based two drug regimens (DTG-2DR) for 620 people [total cohort 3133 (19.8%)]. Method: Clinic database search 1 January 15 to 31 October 21. Demographic, tolerability and HIV related data… read more here.
Keywords: two drug; dtg 3tc; dtg rpv; dtg ... See more keywords
Comparison between the two drug regimens of PPI+Amoxicillin+ Rifampicin and PPI+Amoxicillin+ Levofloxacin for the treatment of H. pylori infections resistant to the first line drug regimen among patients referred to Ilam clinics
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology and Hepatology From Bed to Bench"
DOI: 10.22037/ghfbb.v12i3.1500
Abstract: Aim: This study compares the effects of two drug regimens for Helicobacter pylori (H. pylori) infection resistant to the first line drug regimen among patients referred to Ilam clinics, Iran. Background: Single drug regimen is… read more here.
Keywords: drug regimen; drug; treatment; ppi amoxicillin ... See more keywords
Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00089
Abstract: Human immune system mice are highly valuable for in vivo dissection of human immune responses. Although they were employed for analyzing tuberculosis (TB) disease, there is little data on the spatial organization and cellular composition… read more here.
Keywords: drug regimens; pathology; model; human immune ... See more keywords
Drug Regimens of Novel Antibiotics in Critically Ill Patients with Varying Renal Functions: A Rapid Review
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DOI: 10.3390/antibiotics11050546
Abstract: There is currently an increase in the emergence of multidrug-resistant bacteria (MDR) worldwide, requiring the development of novel antibiotics. However, it is not only the choice of antibiotic that is important in treating an infection;… read more here.
Keywords: ill patients; regimens novel; critically ill; novel antibiotics ... See more keywords
Trajectories of CD4+/CD8+ T-Cells Ratio 96 Weeks after Switching to Dolutegravir-Based Two-Drug Regimens: Results from a Multicenter Prospective Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112315
Abstract: The aim of the present study was to evaluate CD4/CD8 dynamics in patients on dolutegravir (DTG)-based two-drug regimens (2DRs) and compare them with DTG-containing triple-drug regimens (3DRs). A prospective observational study was performed in the… read more here.
Keywords: cd4 cd8; dtg; group; drug regimens ... See more keywords