Active Regulation of On‐Demand Drug Delivery by Magnetically Triggerable Microspouters
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201604558
Abstract: Triggerable devices capable of on-demand, controlled release of therapeutics are attractive options for the treatment of local diseases because of their potential to enhance therapeutic effectiveness with reduced systemic toxicity. Here, the design and fabrication… read more here.
Keywords: delivery; drug; demand; drug release ... See more keywords
Flexible Drug Release Device Powered by Triboelectric Nanogenerator
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201909886
Abstract: Drug release devices of small molecules are widely used in cell stimulation, drug delivery, and microenvironment regulation. Herein, a flexible drug release device (FDRD) powered by a triboelectric nanogenerator (TENG) is demonstrated, that has the… read more here.
Keywords: powered triboelectric; drug; release; release device ... See more keywords
Controllably Switched Drug Release from Successively Dual‐Targeted Nanoreservoirs
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DOI: 10.1002/adhm.201600919
Abstract: The development of a nanocarrier with a capacity of releasing therapeutic agent "on demand" is of great importance for enhancing drug efficacy and reducing its side effect. Here, a multifunctional mesoporous silica nanoparticle is presented… read more here.
Keywords: controllably switched; drug; drug release; release successively ... See more keywords
ROS-Responsive Blended Nanoparticles: Cascade-Amplifying Synergistic Effects of Sonochemotherapy with On-demand Boosted Drug Release During SDT Process.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900720
Abstract: Sonodynamic therapy (SDT) not only has greater tissue-penetrating depth compared to photo-stimulated therapies, but also can also trigger rapid drug release to achieve synergistic sonochemotherapy. Here, reactive oxygen species (ROS)-responsive IR780/PTL- nanoparticles (NPs) are designed… read more here.
Keywords: drug release; sdt; ir780 ptl; ros responsive ... See more keywords
Polytonic drug release via multi- hierarchical microstructures enabled by nano-metamaterials.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202826
Abstract: We introduced "nano-metamaterials", rationally designed novel class metamaterials with multilevel microarchitectures and both characteristic sizes and whole sizes at nanoscale, into the area of drug delivery system, and the relationship between release profile and treatment… read more here.
Keywords: cell; drug release; release; nano metamaterials ... See more keywords
Sustained-Drug-Release, Strong, and Anti-Swelling Water-Lipid Biphasic Hydrogels Prepared via Digital Light Processing 3D Printing for Protection against Osteoarthritis: Demonstration in a Porcine Model.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203236
Abstract: Osteoarthritis is a serious disease affecting joint cartilage. Owing to poor blood supply, the meniscus and acetabular labrum of joints heal poorly after injury. However, the development of artificial alternatives to these components that have… read more here.
Keywords: water lipid; water; drug release; digital light ... See more keywords
A Biomimetic Lubricating Nanosystem with Responsive Drug Release for Osteoarthritis Synergistic Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202203245
Abstract: Osteoarthritis (OA) is associated with lubrication failure of articular cartilage and severe inflammatory response of joint capsule. Synergistic therapy combining joint lubrication and anti‐inflammation emerges as a novel treatment of OA. In this study, bioinspired… read more here.
Keywords: synergistic therapy; drug release; responsive drug;
Disulfide-Bridged Dendritic Organosilicas-Based Biodegradable Molecularly Imprinted Polymers for Multiple Targeting and pH/Redox-responsive Drug Release Toward Chemical/Photodynamic Synergistic Tumor Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300184
Abstract: In this study, a sialic acid (SA) and transferrin (TF) imprinted biodegradable disulfide bridging organosilicas-based drug delivery system (SS-DMONS/DOX-Ce6@MIPs) for targeted cancer therapy was constructed, for the first time. Disulfide bridged dendritic mesoporous organosilicas nanoparticles… read more here.
Keywords: chemical photodynamic; responsive drug; therapy; drug release ... See more keywords
A 3D Tumor‐Mimicking In Vitro Drug Release Model of Locoregional Chemoembolization Using Deep Learning‐Based Quantitative Analyses
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DOI: 10.1002/advs.202206195
Abstract: Primary liver cancer, with the predominant form as hepatocellular carcinoma (HCC), remains a worldwide health problem due to its aggressive and lethal nature. Transarterial chemoembolization, the first‐line treatment option of unresectable HCC that employs drug‐loaded… read more here.
Keywords: tumor mimicking; release model; drug; drug release ... See more keywords
Synthesis and characterization of 2-hydroxyethylmethacrylate/2-(3-indol-yl)ethylmethacrylamide-based novel hydrogels as drug carrier with in vitro antibacterial properties
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45550
Abstract: In this study, a new cationic monomer 2-(3-indol-yl)ethylmethacrylamide (IEMA) derived from tryptamine was synthesized in a single step and characterized by Fourier transform infrared (FTIR), 1H-NMR, and 13C-NMR. Then, one-step preparation of novel poly(2-hydroxyethylmethacrylate-c-2-(3-indol-yl)ethylmethacrylamide), or… read more here.
Keywords: hydroxyethylmethacrylate; drug; indol ethylmethacrylamide; drug release ... See more keywords
Green synthesis of pregabalin-stabilized gold nanoclusters and their applications in sensing and drug release.
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100426
Abstract: This is the first report on the simple preparation of gold nanoclusters stabilized with pregabalin (PREG) as a capping and reducing agent. PREG is an active pharmaceutical ingredient of the commercially available drug "Lyrica" used… read more here.
Keywords: drug; preg auncs; drug release; synthesis ... See more keywords