Stimuli-sensitive crosslinked hydrogels as drug delivery systems: Impact of the drug on the responsiveness.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119157
Abstract: Responsiveness of drug delivery systems (DDS) against internal and external stimuli attracts wide interest as a mechanism that can provide both site-specific release at the target place and feedback regulated release rate. Biological environment is… read more here.
Keywords: drug responsiveness; impact drug; drug delivery; delivery systems ... See more keywords
Microchamber Cultures of Bladder Cancer: A Platform for Characterizing Drug Responsiveness and Resistance in PDX and Primary Cancer Cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12543-9
Abstract: Precision cancer medicine seeks to target the underlying genetic alterations of cancer; however, it has been challenging to use genetic profiles of individual patients in identifying the most appropriate anti-cancer drugs. This spurred the development… read more here.
Keywords: medicine; drug responsiveness; responsiveness resistance; cancer cells ... See more keywords
Antipsychotic Drug Responsiveness and Dopamine Receptor Signaling; Old Players and New Prospects
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2018.00702
Abstract: Antipsychotic drugs targeting dopamine neurotransmission are still the principal mean of therapeutic intervention for schizophrenia. However, about one third of people do not respond to dopaminergic antipsychotics. Genome wide association studies (GWAS), have shown that… read more here.
Keywords: drug responsiveness; antipsychotic drug; dopamine; new prospects ... See more keywords
A Deep Learning Model for Cell Growth Inhibition IC50 Prediction and Its Application for Gastric Cancer Patients
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20246276
Abstract: Heterogeneity in intratumoral cancers leads to discrepancies in drug responsiveness, due to diverse genomics profiles. Thus, prediction of drug responsiveness is critical in precision medicine. So far, in drug responsiveness prediction, drugs’ molecular “fingerprints”, along… read more here.
Keywords: drug responsiveness; drug; cancer; cell ... See more keywords