Improving Anticancer Drug Selection and Prioritization via Neural Learning to Rank
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.3c01060
Abstract: Personalized cancer treatment requires a thorough understanding of complex interactions between drugs and cancer cell lines in varying genetic and molecular contexts. To address this, high-throughput screening has been used to generate large-scale drug response… read more here.
Keywords: drug; drug selection; cell lines; selection prioritization ... See more keywords
Abstract 566: A pathway based drug selection for cancer precision medicine
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-566
Abstract: Background and Purpose: Precision medicine tailors the right therapy to the right patient based on his/her tumor molecular profiles. In clinic and ongoing clinical trials, drug-targeted selection schemes depends more or less on drug targets’… read more here.
Keywords: medicine; precision medicine; drug selection; drug ... See more keywords
Improvement of an in vitro drug selection method for generating transgenic Plasmodium berghei parasites
Sign Up to like & getrecommendations! Published in 2019 at "Malaria Journal"
DOI: 10.1186/s12936-019-2851-6
Abstract: BackgroundReverse genetics approaches have become powerful tools to dissect the biology of malaria parasites. In a previous study, development of an in vitro drug selection method for generating transgenic parasite of Plasmodium berghei was reported.… read more here.
Keywords: drug selection; method; selection; berghei ... See more keywords