High Diastolic Sodium Influx in Heart Failure has Drug-Sensitivities Like Late Sodium Current, but Produces Inward Current at Diastolic Potentials
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1802
Abstract: Heart failure (HF) affects over 6 million people, enhances arrhythmogenesis and is associated with elevated intracellular [Na] ([Na]i), which impacts Ca handling via Na/Ca exchange. HF myocytes exhibit increased late Na current (INaL), typically insufficient… read more here.
Keywords: inward current; sodium; heart failure; sensitivities like ... See more keywords
Changing Antimalarial Drug Sensitivities in Uganda
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01516-17
Abstract: ABSTRACT Dihydroartemisinin-piperaquine (DP) has demonstrated excellent efficacy for the treatment and prevention of malaria in Uganda. However, resistance to both components of this regimen has emerged in Southeast Asia. The efficacy of artemether-lumefantrine, the first-line… read more here.
Keywords: 2010 2013; antimalarial drug; drug; sensitivity ... See more keywords