Evaluation of Publication of Pediatric Drug Trials
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.5829
Abstract: This cross-sectional study assesses the rate of publication of pediatric drug trials and examines the information lost when trials are not published. read more here.
Keywords: pediatric drug; evaluation publication; drug trials; publication pediatric ... See more keywords
Evaluation of Drug Trials in High-, Middle-, and Low-Income Countries and Local Commercial Availability of Newly Approved Drugs
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.7075
Abstract: Key Points Question How commonly are drugs commercially available in the countries where they were tested? Findings This cross-sectional study found that 5 years after their approval in the US, 15% of novel drugs (5… read more here.
Keywords: drug trials; evaluation drug; high middle; trials high ... See more keywords
Assessment of frequency and reporting of design changes among clinical drug trials published in influential medical journals.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2019.08.009
Abstract: BACKGROUND Modifications of primary outcome measures after trial initiation can undermine their scientific validity. We aimed to quantify these changes and to characterize potential predictors in clinical drug trials published in high impact factor general… read more here.
Keywords: medicine; primary outcome; drug trials; clinical drug ... See more keywords
Clinical Drug Trials
Sign Up to like & getrecommendations! Published in 2018 at "Pediatrics in Review"
DOI: 10.1542/pir.2016-0230
Abstract: 1. Amy Mason, MD, MSc* 1. *Bayer Pharmaceuticals, Whippany, NJ 1. Code of Federal Regulations Title 21, Part 312, Investigational New Drug Application. US Food and Drug Administration. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?CFRPart=312. Accessed January 24, 2018 2. The… read more here.
Keywords: https www; drug trials; drug; clinical drug ... See more keywords
Review of Advanced Drug Trials Focusing on the Reduction of Brain Beta-Amyloid to Prevent and Treat Dementia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Experimental Pharmacology"
DOI: 10.2147/jep.s265626
Abstract: Abstract Alzheimer disease (AD) is the most common neurodegenerative disease and typically affects patients older than age 65. Around this age, the number of neurons begins to gradually decrease in healthy brains, but brains of… read more here.
Keywords: beta; review advanced; brain; advanced drug ... See more keywords
Geriatric drug trials on solid tumor are scarce worldwide
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1063648
Abstract: Background Conducting geriatric trials is the most feasible way to address the vast underrepresentation of older adults in clinical trials of cancer therapies. This study is a globally comprehensive examination of geriatric trials for solid… read more here.
Keywords: trials solid; solid tumor; geriatric trials; drug ... See more keywords
The Impact of Drug Trials With Financial Conflict of Interests on the Meta-analyses: A Meta-epidemiological Study.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of health policy and management"
DOI: 10.34172/ijhpm.2021.162
Abstract: BACKGROUND To assess the impact of trials with potential financial conflict of interests (FCOIs) on evidence synthesis in meta-analyses (MAs). METHODS A total of 96 MAs from the Cochrane Library about drug trials were investigated.… read more here.
Keywords: meta epidemiological; drug trials; meta analyses; financial conflict ... See more keywords
Analysis of clinical drug trials in children compared to clinical drug trials in adults, in Argentina.
Sign Up to like & getrecommendations! Published in 2019 at "Archivos argentinos de pediatria"
DOI: 10.5546/aap.2019.eng.34
Abstract: INTRODUCTION It is necessary to know the extent and subject matter of pediatric clinical drug research in Argentina and establish the differences with the adult population. OBJECTIVES To compare adult and pediatric clinical drug trials… read more here.
Keywords: child mortality; drug trials; infant child; drug ... See more keywords