Bio-inspired microneedle design for efficient drug/vaccine coating
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical Microdevices"
DOI: 10.1007/s10544-019-0456-z
Abstract: Biomimetics is the interdisciplinary scientific field focused on the study and imitation of biological systems, with the aim of solving complex technological problems. In this paper, we present a new bio-inspired design for microneedles (MNs)… read more here.
Keywords: drug vaccine; inspired microneedle; bio inspired; drug ... See more keywords
SARS-CoV-2: Insights into its structural intricacies and functional aspects for drug and vaccine development
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2021.02.212
Abstract: Globally, SARS-CoV-2 has emerged as threat to life and economy. Researchers are trying to find a cure against this pathogen but without much success. Several attempts have been made to understand the atomic level details… read more here.
Keywords: sars cov; drug vaccine; vaccine development;
The growing complexity of COVID-19 drug and vaccine candidates: challenges and critical transitions
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Infection and Public Health"
DOI: 10.1016/j.jiph.2020.12.009
Abstract: COVID-19 has nowadays affected almost all our societies and global health systems. The latest deadly pandemic has heavily influenced both life and livelihood worldwide. SARS-CoV-2 is the causative organism of COVID-19, that is spreading and… read more here.
Keywords: complexity covid; drug vaccine; covid drug; drug ... See more keywords
Zika virus reservoirs: Implications for transmission, future outbreaks, drug and vaccine development
Sign Up to like & getrecommendations! Published in 2017 at "F1000Research"
DOI: 10.12688/f1000research.12695.1
Abstract: Zika virus (ZIKV) was recently declared as a ‘Global Health Emergency’ by the World Health Organization. Various tissue reservoirs of ZIKV in infected humans and animals models have been observed, the implications of which are… read more here.
Keywords: drug vaccine; zikv; zika virus; virus ... See more keywords
Leishmaniasis in humans: drug or vaccine therapy?
Sign Up to like & getrecommendations! Published in 2018 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s146521
Abstract: Leishmania is an obligate intracellular pathogen that invades phagocytic host cells. Approximately 30 different species of Phlebotomine sand flies can transmit this parasite either anthroponotically or zoonotically through their bites. Leishmaniasis affects poor people living… read more here.
Keywords: drug; leishmaniasis; drug vaccine; therapy leishmaniasis ... See more keywords
Dissecting the Mycobacterium bovis BCG Response to Macrophage Infection to Help Prioritize Targets for Anti-Tuberculosis Drug and Vaccine Discovery
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10010113
Abstract: New strategies are required to reduce the worldwide burden of tuberculosis. Intracellular survival and replication of Mycobacterium tuberculosis after macrophage phagocytosis is a fundamental step in the complex host–pathogen interactions that lead to granuloma formation… read more here.
Keywords: mycobacterium; infection; drug vaccine; vaccine discovery ... See more keywords
Evidence of episodic positive selection in Corynebacterium diphtheriae complex of species and its implementations in identification of drug and vaccine targets
Sign Up to like & getrecommendations! Published in 2022 at "PeerJ"
DOI: 10.7717/peerj.12662
Abstract: Background Within the pathogenic bacterial species Corynebacterium genus, six species that can produce diphtheria toxin (C. belfantii, C. diphtheriae, C. pseudotuberculosis, C. rouxii, C. silvaticum and C. ulcerans) form a clade referred to as the… read more here.
Keywords: positive selection; drug; drug vaccine; complex species ... See more keywords