Unveiling New Druggable Pockets in Influenza Non-Structural Protein 1: NS1–Host Interactions as Antiviral Targets for Flu
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DOI: 10.3390/ijms24032977
Abstract: Influenza viruses are responsible for significant morbidity and mortality worldwide in winter seasonal outbreaks and in flu pandemics. Influenza viruses have a high rate of evolution, requiring annual vaccine updates and severely diminishing the effectiveness… read more here.
Keywords: druggable pockets; structural protein; protein ns1; non structural ... See more keywords
Proteome-Wide Identification and Comparison of Drug Pockets for Discovering New Drug Indications and Side Effects
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DOI: 10.3390/molecules30020260
Abstract: Drug development faces significant financial and time challenges, highlighting the need for more efficient strategies. This study evaluated the druggability of the entire human proteome using Fpocket. We identified 15,043 druggable pockets in 20,255 predicted… read more here.
Keywords: drug pockets; proteome wide; indications side; drug ... See more keywords