Articles with "drugging protein" as a keyword



DREAMM: a web-based server for drugging protein-membrane interfaces as a novel workflow for targeted drug design

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Published in 2022 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btac680

Abstract: Abstract Summary The allosteric modulation of peripheral membrane proteins (PMPs) by targeting protein-membrane interactions with drug-like molecules represents a new promising therapeutic strategy for proteins currently considered undruggable. However, the accessibility of protein-membrane interfaces by… read more here.

Keywords: membrane interfaces; dreamm; membrane; drugging protein ... See more keywords