Challenges and Strategies for Quantification of Drugs in the Brain: Current Scenario and Future Advancement.
Sign Up to like & getrecommendations! Published in 2020 at "Critical reviews in analytical chemistry"
DOI: 10.1080/10408347.2020.1791041
Abstract: The site of action of centrally acting drugs lies inside the brain and therefore, needs to reach the brain to exert their therapeutic efficacy. Discovery and development process of such types of drugs demands their… read more here.
Keywords: strategies quantification; quantification drugs; inside brain; drugs brain ... See more keywords
Antihypertensive drugs and brain function: mechanisms underlying therapeutically beneficial and harmful neuropsychiatric effects
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvac110
Abstract: Abstract A bidirectional relationship exists between hypertension and psychiatric disorders, including unipolar and bipolar depression, anxiety, post-traumatic stress disorder (PTSD), psychosis, schizophrenia, mania, and dementia/cognitive decline. Repurposing of antihypertensive drugs to treat mental disorders is… read more here.
Keywords: brain function; brain; function mechanisms; antihypertensive drugs ... See more keywords