Cost Effectiveness of Pharmacogenetic Testing for Drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2754
Abstract: The objective of this study was to evaluate the evidence on cost‐effectiveness of pharmacogenetic (PGx)–guided treatment for drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines. A systematic review was conducted using multiple biomedical literature databases… read more here.
Keywords: drugs clinical; pharmacogenetics implementation; effectiveness pharmacogenetic; cost ... See more keywords
Investigational drugs in clinical trials for Hidradenitis Suppurativa
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2018.1412430
Abstract: ABSTRACT Introduction: Hidradenitis suppurativa is a chronic skin disease with a significant unmet need for treatment options. Randomized controlled trials are few and only a single drug (adalimumab) has Hidradenitis as a registered indication. Areas… read more here.
Keywords: investigational drugs; hidradenitis suppurativa; clinical trials; drugs clinical ... See more keywords
Experimental drugs in clinical trials for acute myeloid leukemia: innovations, trends, and opportunities
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2023.2171860
Abstract: ABSTRACT Introduction Acute myeloid leukemia (AML) is a heterogeneous disease characterized by many cytogenetic and molecular alterations. Due to better knowledge of the molecular basis of AML, many targeted therapies have been introduced and registered,… read more here.
Keywords: drugs clinical; myeloid leukemia; acute myeloid; experimental drugs ... See more keywords
Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review
Sign Up to like & getrecommendations! Published in 2019 at "BioMed Research International"
DOI: 10.1155/2019/1212369
Abstract: B-cell lymphoma 2 (Bcl-2) is a regulator protein involved in apoptosis. In the past few decades, this protein has been demonstrated to have high efficacy in cancer therapy, and several approaches targeting Bcl-2 have been… read more here.
Keywords: protein; approaches targeting; bcl inhibitors; review ... See more keywords