Multistage-Responsive Nanocomplexes Attenuate Ulcerative Colitis by Improving the Accumulation and Distribution of Oral Nucleic Acid Drugs in the Colon.
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DOI: 10.1021/acsami.1c21595
Abstract: Oral gene therapy has emerged as a potential optimal treatment for ulcerative colitis (UC). Nucleic acid drugs possessing versatility can not only inhibit inflammation but realize colon mucosal healing, fulfilling the clinical objective of UC… read more here.
Keywords: acid drugs; drugs colon; accumulation; nucleic acid ... See more keywords