Review on predicting pairwise relationships between human microbes, drugs and diseases: from biological data to computational models
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac080
Abstract: In recent years, with the rapid development of techniques in bioinformatics and life science, a considerable quantity of biomedical data has been accumulated, based on which researchers have developed various computational approaches to discover potential… read more here.
Keywords: microbes drugs; diseases biological; data computational; biological data ... See more keywords
Network approaches for modeling the effect of drugs and diseases
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac229
Abstract: Abstract The network approach is quickly becoming a fundamental building block of computational methods aiming at elucidating the mechanism of action (MoA) and therapeutic effect of drugs. By modeling the effect of drugs and diseases… read more here.
Keywords: network; effect drugs; drug; modeling effect ... See more keywords
Drug repositioning through integration of prior knowledge and projections of drugs and diseases
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz182
Abstract: MOTIVATION Identifying and developing novel therapeutic effects for existing drugs contributes to reduction of drug development costs. Most of the previous methods focus on integration of the heterogeneous data of drugs and diseases frommultiple sources… read more here.
Keywords: drug; prior knowledge; drug disease; drugs diseases ... See more keywords