Semi-Mechanistic Model for Predicting the Dosing Rate in Children and Neonates for Drugs Mainly Eliminated by Cytochrome Metabolism
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DOI: 10.1007/s40262-017-0596-3
Abstract: Background and ObjectiveA simple approach is proposed to predict drug clearance in children when no paediatric data are available for drugs metabolised by cytochromes.MethodsThe maturation functions of cytochrome activity and binding proteins in plasma were… read more here.
Keywords: eliminated cytochrome; drugs mainly; mainly eliminated; model ... See more keywords