Bioanalysis of drugs and their metabolites by chiral electromigration techniques (2010–2020)
Sign Up to like & getrecommendations! Published in 2021 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202000383
Abstract: The further development and application of capillary electromigration techniques for the enantioselective determination of drugs and their metabolites in body fluids, tissues, and in vitro preparations during the 2010 to 2020 time period continued to… read more here.
Keywords: drugs metabolites; 2010 2020; electromigration techniques; bioanalysis ... See more keywords
Development and application of the analytical method for illicit drugs and metabolites in fish tissues.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.06.018
Abstract: In this study, we developed a screening method for highly accurate and sensitive analysis of 12 illicit drugs and metabolites in fish tissues. The approach was based on ultrasonic-assisted extraction and solid phase extraction, followed… read more here.
Keywords: drugs metabolites; fish tissues; method; illicit drugs ... See more keywords
Nontargeted screening method for veterinary drugs and their metabolites based on fragmentation characteristics from ultrahigh-performance liquid chromatography-high-resolution mass spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2021.130928
Abstract: Nontargeted screening of both veterinary drugs and their metabolites is important for comprehensive safety evaluation of animal-derived foods. In this study, a novel nontargeted screening strategy was developed for veterinary drugs and their metabolites based… read more here.
Keywords: drugs metabolites; veterinary drugs; mass; nontargeted screening ... See more keywords
Optimization of chromatographic systems for analysis of selected psychotropic drugs and their metabolites in serum and saliva by HPLC in order to monitor therapeutic drugs
Sign Up to like & getrecommendations! Published in 2019 at "Open Chemistry"
DOI: 10.1515/chem-2019-0152
Abstract: Abstract Retention, separation selectivity and system efficiency of selected basic psychotropic drugs (clozapine, aripiprazole, vortioxetine and zolpidem) and drug metabolites (desmethylclozapine, clozapine N-oxide and dehydroaripiprazole) on Hydro RP, Phenyl-Hexyl and Polar RP columns were studied.… read more here.
Keywords: serum saliva; analysis; drugs metabolites; psychotropic drugs ... See more keywords
Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19
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DOI: 10.3390/ijms22041797
Abstract: Lysosomotropism is a biological characteristic of small molecules, independently present of their intrinsic pharmacological effects. Lysosomotropic compounds, in general, affect various targets, such as lipid second messengers originating from lysosomal enzymes promoting endothelial stress response… read more here.
Keywords: drugs metabolites; covid; lysosomotropic; sars cov ... See more keywords
Evaluation of OptiFlow™-MS/MS for bioanalysis of pharmaceutical drugs and metabolites.
Sign Up to like & getrecommendations! Published in 2020 at "Bioanalysis"
DOI: 10.4155/bio-2019-0250
Abstract: Aim: Microflow tandem mass spectrometry-based methods have been proposed as options to improve sensitivity and selectivity while improving sample utility and solvent consumption. Here, we evaluate a newly introduced microflow source, OptiFlow™, for quantitative performance.… read more here.
Keywords: drugs metabolites; bioanalysis; optiflow bioanalysis; evaluation optiflow ... See more keywords
Recent advances in electrochemical sensors and biosensors for monitoring drugs and metabolites in pharmaceutical and biological samples
Sign Up to like & getrecommendations! Published in 2023 at "ADMET and DMPK"
DOI: 10.5599/admet.1709
Abstract: Various applications of electrochemical sensors and biosensors have been reported in many fields. These include pharmaceuticals, drug detection, cancer detection, and analysis of toxic elements in tap water. Electrochemical sensors are characterised by their low… read more here.
Keywords: pharmaceutical biological; carbon; metabolites pharmaceutical; electrochemical sensors ... See more keywords