Statins: Old drugs as new therapy for liver diseases?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2018.07.019
Abstract: In addition to lowering cholesterol levels, statins have pleiotropic effects, particularly anti-inflammatory, antiangiogenic, and antifibrotic, that may be beneficial in some chronic inflammatory conditions. Statins have only recently been investigated as a potential treatment option… read more here.
Keywords: old drugs; statins old; liver diseases; treatment ... See more keywords
Transformation of Amphiphilic Antiviral Drugs into New Dimensional Nanovesicles Structures
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c05758
Abstract: Improved techniques were applied to formulate drugs into dimensional nanostructures, doped “nanovesicles”. These nanovesicles are solely composed of self-assembled amphiphilic antiviral agents used for the treatment of viral infections caused by flaviviruses, such as Zika… read more here.
Keywords: dimensional nanovesicles; amphiphilic antiviral; drugs new; transformation amphiphilic ... See more keywords
Antimalarial drugs: what’s new in the patents?
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Therapeutic Patents"
DOI: 10.1080/13543776.2023.2203814
Abstract: ABSTRACT Introduction The efficacy of current therapeutic warheads in preventing malaria transmission or treating the disease is often hampered by the emergence of drug-resistance. No effective vaccines are available to date, and novel drugs able… read more here.
Keywords: patents antimalarial; new patents; antimalarial drugs; drugs new ... See more keywords
New drugs and new toxicities: pembrolizumab-induced myocarditis
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-223252
Abstract: Pembrolizumab is an immune checkpoint inhibitor that significantly improves clinical outcomes in numerous solid organ malignancies. Despite successful therapeutic responses, this new drug comes with a constellation of adverse reactions. Herein, we chronicle the case… read more here.
Keywords: toxicities pembrolizumab; new toxicities; induced myocarditis; pembrolizumab induced ... See more keywords
Psychedelics: Old drugs, new trips
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Psychopharmacology"
DOI: 10.1177/02698811211003495
Abstract: This special edition of the Journal of Psychopharmacology continues a reflection of psychopharmacology’s vogue to breathe new life into old drugs. The shimmer of psychedelia is back from the grave of legal prohibition, seemingly to… read more here.
Keywords: old drugs; ht2a; psychedelics old; psychopharmacology ... See more keywords
Challenges in severe asthma: Do we need new drugs or new biomarkers?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.921967
Abstract: Severe asthma is a complex, heterogenous airway condition. There have been significant advances in severe asthma management in the past decade using monoclonal antibody therapies that target the inflammatory component of the disease. Patient selection… read more here.
Keywords: new drugs; drugs new; asthma need; need new ... See more keywords
Antagonists of Vitamin K—Popular Coumarin Drugs and New Synthetic and Natural Coumarin Derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25061465
Abstract: Many natural coumarins and their chemically synthesized analogs and derivatives exert diverse properties, such as anticancer, antioxidant, anti-inflammatory, or anticoagulant, with the latter being of the utmost importance. The widely used warfarin, acenocoumarol, and phenprocoumon… read more here.
Keywords: vitamin popular; coumarin drugs; coumarin; antagonists vitamin ... See more keywords
Three-dimensional drugs: A new era in the pharmaceutical development
Sign Up to like & getrecommendations! Published in 2017 at "Indian Journal of Pharmacology"
DOI: 10.4103/ijp.ijp_119_18
Abstract: Since long, two dimensional printing technologies (flexographic printing and inkjet technology) are being applied in the pharmaceutical sector and inclusion of three dimensional (3D) printing technology in the same field is relatively new.[1] 3D printing… read more here.
Keywords: three dimensional; drugs new; new era; era pharmaceutical ... See more keywords