Cystic fibrosis drugs target the malformed proteins at the root of the disease
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DOI: 10.1038/d41586-020-02106-w
Abstract: New combinations of molecules put many patients on the path to good health. But those with rarer mutations are, for now, left behind. New combinations of molecules put many patients on the path to good… read more here.
Keywords: malformed proteins; cystic fibrosis; target malformed; fibrosis drugs ... See more keywords
Drugs that target aging: how do we discover them?
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DOI: 10.1080/17460441.2019.1597049
Abstract: ABSTRACT Introduction: Biology of aging is focused on elucidating the biochemical and genetic pathways that contribute to cellular damage accumulation over time. Thirty years of research are beginning to bear fruit as the first pharmacological… read more here.
Keywords: research; biology aging; drugs target; biology ... See more keywords
A preclinical assessment to repurpose drugs to target type 1 diabetes‐associated type B coxsackieviruses
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DOI: 10.1111/dme.14175
Abstract: To screen several antiviral drugs systematically for their efficacy against type B coxsackieviruses. read more here.
Keywords: assessment repurpose; drugs target; repurpose drugs; preclinical assessment ... See more keywords