Artemisinin-type drugs for the treatment of hematological malignancies
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DOI: 10.1007/s00280-020-04170-5
Abstract: Qinghaosu, known as artemisinin (ARS), has been for over two millennia, one of the most common herbs prescribed in traditional Chinese medicine (TCM). ARS was developed as an antimalarial drug and currently belongs to the… read more here.
Keywords: medicine; artemisinin type; hematological malignancies; type drugs ... See more keywords
Investigational antiviral drugs for the treatment of COVID-19 patients.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of virology"
DOI: 10.1007/s00705-022-05368-z
Abstract: In the current pandemic of coronavirus disease 2019 (COVID-19), antiviral drugs are at the center of attention because of their critical role against severe acute respiratory disease syndrome coronavirus 2 (SARS-CoV-2). In addition to designing… read more here.
Keywords: investigational antiviral; drugs treatment; antiviral drugs; covid ... See more keywords
A Scoping Review Protocol to Explore the Use of Interleukin-1-Targeting Drugs for the Treatment of Dermatological Diseases: Indications, Mechanism of Action, Efficacy, and Safety
Sign Up to like & getrecommendations! Published in 2018 at "Dermatology and Therapy"
DOI: 10.1007/s13555-018-0235-4
Abstract: IntroductionThe interleukin (IL)-1 pathway has been identified as being involved in inflammatory and neoplastic skin diseases such as psoriasis, atopic dermatitis, neutrophilic dermatosis, melanoma, and squamous cell carcinoma. Drugs developed to target the IL-1 pathway… read more here.
Keywords: methodology; treatment dermatological; dermatology; evidence ... See more keywords
Hepatitis C - New drugs and treatment prospects.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.01.025
Abstract: Hepatitis C virus (HCV) affects approx. 3% of the world's population and accounts for ca 300 000 deaths per year. 80% of individuals with HCV develop chronic symptoms which, when untreated, may cause cirrhosis (27%) or… read more here.
Keywords: treatment; hcv; hepatitis new; treatment prospects ... See more keywords
Drugs for the treatment of glaucoma: Targets, structure-activity relationships and clinical research.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113842
Abstract: Glaucoma is the third leading cause of blindness and impairment of vision worldwide, after refractive errors and cataracts. According to the survey, the number of people with glaucoma is more than 76 million, with projections… read more here.
Keywords: glaucoma; structure activity; treatment glaucoma; targets structure ... See more keywords
Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China
Sign Up to like & getrecommendations! Published in 2020 at "Virus Research"
DOI: 10.1016/j.virusres.2020.198057
Abstract: Abstract The fight against the novel coronavirus pneumonia (namely COVID-19) that seriously harms human health is a common task for all mankind. Currently, development of drugs against the novel coronavirus (namely SARS-CoV-2) is quite urgent.… read more here.
Keywords: coronavirus pneumonia; novel coronavirus; coronavirus; covid ... See more keywords
Drugs for the Treatment of Zika Virus Infection.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b00775
Abstract: Zika virus is an emerging flavivirus that causes the neurodevelopmental congenital Zika syndrome and that has been linked to the neuroinflammatory Guillain-Barré syndrome. The absence of a vaccine or a clinically-approved drug to treat the… read more here.
Keywords: drug; treatment zika; zika virus; virus infection ... See more keywords
Experimental and investigational drugs for the treatment of anal cancer
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2018.1543659
Abstract: ABSTRACT Introduction: Squamous cell carcinoma of the anal canal (SCCA) is a rare malignancy, but its incidence rates have been increasing in the last decade. Studies have demonstrated that up to 47% of patients with… read more here.
Keywords: treatment anal; experimental investigational; investigational drugs; treatment ... See more keywords
Current options and investigational drugs for the treatment of eosinophilic esophagitis
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DOI: 10.1080/13543784.2022.2033207
Abstract: ABSTRACT Introduction Current treatments of eosinophilic esophagitis (EoE) induce symptomatic and histological remission in a proportion of patients. However, they do not fully meet patients’ needs and limitations should be acknowledged. The growing epidemiology of… read more here.
Keywords: investigational drugs; eosinophilic esophagitis; current options; drugs treatment ... See more keywords
Investigational drugs for the treatment of thymic cancer: a focus on phase 1 and 2 clinical trials
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2113373
Abstract: ABSTRACT Introduction Thymic epithelial tumors (TETs) are rare tumors of thymic epithelial cells. Treatment options for advanced disease patients who failed standard platinum-based chemotherapy are limited. Areas covered Phase I and II trials published in… read more here.
Keywords: investigational drugs; clinical trials; thymic cancer; treatment thymic ... See more keywords
Emerging drugs for the treatment of neuromyelitis optica
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DOI: 10.1080/14728214.2020.1803828
Abstract: ABSTRACT Introduction Evidence-based treatment options for neuromyelitis optica spectrum disorders (NMOSD) patients are beginning to enter the market. Where previously, there was only the exclusive use of empiric and off-label immunosuppressants in this rare and… read more here.
Keywords: treatment neuromyelitis; emerging drugs; treatment; antibody ... See more keywords