Debris buster is a Drosophila scavenger receptor essential for airway physiology.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.08.018
Abstract: Scavenger receptors class B (SR-B) are multifunctional transmembrane proteins, which in vertebrates participate in lipid transport, pathogen clearance, lysosomal delivery and intracellular sorting. Drosophila has 14 SR-B members whose functions are still largely unknown. Here,… read more here.
Keywords: dsb; debris buster; essential airway; physiology ... See more keywords
USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9
Sign Up to like & getrecommendations! Published in 2020 at "Oncogenesis"
DOI: 10.1038/s41389-020-00244-4
Abstract: The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for… read more here.
Keywords: nuclear speckles; dsb; homologous recombination; rna helicase ... See more keywords
RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks
Sign Up to like & getrecommendations! Published in 2021 at "Oncogenesis"
DOI: 10.1038/s41389-021-00315-0
Abstract: Ubiquitination-dependent DNA damage response (DDR) signals play a critical role in the cellular choice of DNA damage repair pathways. Human DNA helicase RecQL4 participates in DNA replication and repair, and loss of RecQL4 is associated… read more here.
Keywords: rnf8; dsb; dna; dna double ... See more keywords
DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2208441119
Abstract: Significance Meiotic recombination is essential for producing genetically diversified haploid gametes and initiates from the programmed formation of double-strand breaks (DSBs), which usually take place in accessible chromatin with features of active transcription in multiple… read more here.
Keywords: meiotic dsb; dna polymerase; transcription; dsb ... See more keywords
Conservation and divergence of meiotic DNA double strand break forming mechanisms in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab715
Abstract: Abstract In the current meiotic recombination initiation model, the SPO11 catalytic subunits associate with MTOPVIB to form a Topoisomerase VI-like complex that generates DNA double strand breaks (DSBs). Four additional proteins, PRD1/AtMEI1, PRD2/AtMEI4, PRD3/AtMER2 and… read more here.
Keywords: prd3 atmer2; dsb; prd2 atmei4; dna double ... See more keywords
Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation
Sign Up to like & getrecommendations! Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae574
Abstract: Abstract Nuclear actin-based movements support DNA double-strand break (DSB) repair. However, molecular determinants that promote filamentous actin (F-actin) formation on the damaged chromatin remain undefined. Here we describe the DYRK1A kinase as a nuclear activity… read more here.
Keywords: actin assembly; dsb; nuclear actin; actin ... See more keywords
Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky088
Abstract: Abstract DNA double-strand breaks (DSBs) are fatal DNA lesions and activate a rapid DNA damage response. However, the earliest stage of DSB sensing remains elusive. Here, we report that PARP1 and the Ku70/80 complex localize… read more here.
Keywords: ku70 complex; dsb; dna; dna double ... See more keywords
Effect of PI3-kinase inhibitors on DNA double strand break repair pathways: observations using a site specific DSB induction system.
Sign Up to like & getrecommendations! Published in 2024 at "Radiation protection dosimetry"
DOI: 10.1093/rpd/ncae074
Abstract: We established two types of site-specific DNA double strand breaks (DSB) induction systems to elucidate factors which affect the efficiency or quality of DSB repair. For mutation assays, a site specific DSB was generated by… read more here.
Keywords: dna double; repair; dsb; site specific ... See more keywords
Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.02.16.480793
Abstract: In the first meiotic cell division, proper segregation of chromosomes in most organisms depends on chiasmata, exchanges of continuity between homologous chromosomes that originate from the repair of programmed double-strand breaks (DSBs) catalyzed by the… read more here.
Keywords: dsb; dsbs; double strand; phosphoregulation dsb ... See more keywords
Reduced Noise Temperatures of a THz NbN Hot Electron Bolometer Mixer
Sign Up to like & getrecommendations! Published in 2025 at "IEEE Transactions on Terahertz Science and Technology"
DOI: 10.1109/tthz.2024.3475010
Abstract: In this article, we measure the double sideband (DSB) receiver noise temperature ($T_{\text{rec}}^{\text{DSB}})$ of an NbN hot electron bolometer (HEB) mixer at three local oscillator frequencies of 1.6, 2.5, and 5.3 THz. The HEB has… read more here.
Keywords: text; tex math; dsb; inline formula ... See more keywords
Susceptibility of Salmonella enterica Typhimurium dry surface biofilms to disinfection
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Food Safety"
DOI: 10.1111/jfs.13117
Abstract: In food preparation and manufacturing environments, surfaces contaminated with Salmonella can lead to outbreaks of Salmonellosis. We hypothesise that Salmonella resides on dry surfaces in a biofilm form leading to potential environmental persistence and transfer… read more here.
Keywords: food; typhimurium; salmonella; dry surface ... See more keywords