Debris buster is a Drosophila scavenger receptor essential for airway physiology.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.08.018
Abstract: Scavenger receptors class B (SR-B) are multifunctional transmembrane proteins, which in vertebrates participate in lipid transport, pathogen clearance, lysosomal delivery and intracellular sorting. Drosophila has 14 SR-B members whose functions are still largely unknown. Here,… read more here.
Keywords: dsb; debris buster; essential airway; physiology ... See more keywords
USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9
Sign Up to like & getrecommendations! Published in 2020 at "Oncogenesis"
DOI: 10.1038/s41389-020-00244-4
Abstract: The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for… read more here.
Keywords: nuclear speckles; dsb; homologous recombination; rna helicase ... See more keywords
RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks
Sign Up to like & getrecommendations! Published in 2021 at "Oncogenesis"
DOI: 10.1038/s41389-021-00315-0
Abstract: Ubiquitination-dependent DNA damage response (DDR) signals play a critical role in the cellular choice of DNA damage repair pathways. Human DNA helicase RecQL4 participates in DNA replication and repair, and loss of RecQL4 is associated… read more here.
Keywords: rnf8; dsb; dna; dna double ... See more keywords
DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2208441119
Abstract: Significance Meiotic recombination is essential for producing genetically diversified haploid gametes and initiates from the programmed formation of double-strand breaks (DSBs), which usually take place in accessible chromatin with features of active transcription in multiple… read more here.
Keywords: meiotic dsb; dna polymerase; transcription; dsb ... See more keywords
Conservation and divergence of meiotic DNA double strand break forming mechanisms in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab715
Abstract: Abstract In the current meiotic recombination initiation model, the SPO11 catalytic subunits associate with MTOPVIB to form a Topoisomerase VI-like complex that generates DNA double strand breaks (DSBs). Four additional proteins, PRD1/AtMEI1, PRD2/AtMEI4, PRD3/AtMER2 and… read more here.
Keywords: prd3 atmer2; dsb; prd2 atmei4; dna double ... See more keywords
Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky088
Abstract: Abstract DNA double-strand breaks (DSBs) are fatal DNA lesions and activate a rapid DNA damage response. However, the earliest stage of DSB sensing remains elusive. Here, we report that PARP1 and the Ku70/80 complex localize… read more here.
Keywords: ku70 complex; dsb; dna; dna double ... See more keywords
Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.02.16.480793
Abstract: In the first meiotic cell division, proper segregation of chromosomes in most organisms depends on chiasmata, exchanges of continuity between homologous chromosomes that originate from the repair of programmed double-strand breaks (DSBs) catalyzed by the… read more here.
Keywords: dsb; dsbs; double strand; phosphoregulation dsb ... See more keywords
The Disulfide Bond Formation Pathway Is Essential for Anaerobic Growth of Escherichia coli
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bacteriology"
DOI: 10.1128/jb.00120-17
Abstract: ABSTRACT Disulfide bonds are critical to the stability and function of many bacterial proteins. In the periplasm of Escherichia coli, intramolecular disulfide bond formation is catalyzed by the two-component disulfide bond forming (DSB) system. Inactivation… read more here.
Keywords: disulfide bond; dsb; bond formation; bond ... See more keywords
Experimental comparison of DSB and CS-DSB mmW formats over a hybrid fiber and FSO fronthaul network for 5G.
Sign Up to like & getrecommendations! Published in 2021 at "Optics express"
DOI: 10.1364/oe.434334
Abstract: The telecommunication world is experiencing the 5th generation (5G) networks deployment including the use of millimeter wave (mmW) frequency bands to satisfy capacity demands. This leads to the extensive use of optical communications, especially the… read more here.
Keywords: transmission; dsb dsb; fronthaul network; dsb ... See more keywords
Position effects influencing intrachromosomal repair of a double-strand break in budding yeast
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0180994
Abstract: Repair of a double-strand break (DSB) by an ectopic homologous donor sequence is subject to the three-dimensional arrangement of chromosomes in the nucleus of haploid budding yeast. The data for interchromosomal recombination suggest that searching… read more here.
Keywords: dsb; position; donor; repair double ... See more keywords
Saccharomyces Boulardii Attenuates Autonomic Cardiovascular Dysfunction and Modulates Inflammatory Cytokines in Diabetic Mice
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes"
DOI: 10.2337/db18-2365-pub
Abstract: The effects of probiotics on blood glucose and cardiovascular complications induced by diabetes have been inconsistent. Therefore, the aim was to assess the effect of Saccharomyces boulardii (Sb) on metabolic and cardiovascular dysfunction in streptozotocin… read more here.
Keywords: dsb; dysfunction; cardiovascular dysfunction; saccharomyces boulardii ... See more keywords