DNA replication and sister chromatid cohesion 1 promotes breast carcinoma progression by modulating the Wnt/β-catenin signaling and p53 protein
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DOI: 10.1007/s12038-020-00100-y
Abstract: The objective of this study is to assess the prognostic and functional role of DSCC1 in breast carcinoma, as well as the potential mechanism. Based upon the TCGA data, the expression pattern and prognostic value… read more here.
Keywords: carcinoma; breast carcinoma; catenin; dscc1 ... See more keywords
MMS22L-TONSL functions in sister chromatid cohesion in a pathway parallel to DSCC1-RFC
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DOI: 10.26508/lsa.202201596
Abstract: A genome-wide CRISPR screen in human DSCC1-knockout cells reveals multiple dependencies, including additive DNA replication defects resulting from POLE3-4 depletion and enhanced sister chromatid cohesion loss following depletion of MMS22L-TONSL. The leading strand–oriented alternative PCNA… read more here.
Keywords: replication; dscc1 rfc; mms22l tonsl; dscc1 ... See more keywords