In systemic lupus erythematosus anti-dsDNA antibodies can promote thrombosis through direct platelet activation.
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DOI: 10.1016/j.jaut.2019.102355
Abstract: Systemic lupus erythematosus (SLE) is associated with a high risk of venous and arterial thrombosis, not necessarily associated with prothrombotic antiphospholipid antibodies (Abs). Alternatively, thrombosis may be due to an increased titer of anti-dsDNA Abs… read more here.
Keywords: thrombosis; dsdna abs; activation; anti dsdna ... See more keywords