Application of temperature-responsive HIS-tag fluorophores to differential scanning fluorimetry screening of small molecule libraries
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DOI: 10.3389/fphar.2022.1040039
Abstract: Differential scanning fluorimetry is a rapid and economical biophysical technique used to monitor perturbations to protein structure during a thermal gradient most often by detecting protein unfolding events through an environment-sensitive fluorophore. By employing an… read more here.
Keywords: dsf assay; temperature; differential scanning; scanning fluorimetry ... See more keywords