Disulfiram-loaded mixed nanoparticles with high drug-loading and plasma stability by reducing the core crystallinity for intravenous delivery.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2018.05.057
Abstract: To develop an injectable formulation and improve the stability of disulfiram (DSF), DSF was encapsulated into mixed nanoparticles (DSF-NPs) through a high-pressure homogenization method. The Flory-Huggins interaction parameters (χFH) were calculated to predict the miscibility… read more here.
Keywords: drug loading; dsf; stability; dsf nps ... See more keywords
Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases
Sign Up to like & getrecommendations! Published in 2021 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-021-00770-w
Abstract: Sepsis is a dysregulated immune response to infection and potentially leads to life-threatening organ dysfunction, which is often seen in serious Covid-19 patients. Disulfiram (DSF), an old drug that has been used to treat alcohol… read more here.
Keywords: inflammatory diseases; inflammatory; disulfiram loaded; dsf nps ... See more keywords