Articles with "dsg3" as a keyword



Cutaneous‐type pemphigus vulgaris might be a transient subtype in pemphigus vulgaris: a case series

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Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"

DOI: 10.1111/jdv.18348

Abstract: Dear Editor Pemphigus vulgaris (PV) is an autoimmune blistering disease involving mainly the mucous membrane with or without cutaneous erosions. In recent years, there have been emerging discussions among the cutaneous-type PV (cPV), which was… read more here.

Keywords: dsg3; auto antibodies; pemphigus vulgaris; auto ... See more keywords

The Diversity of Serum Anti-DSG3 IgG Subclasses Has a Major Impact on Pemphigus Activity and Is Predictive of Relapses After Treatment With Rituximab

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.849790

Abstract: Introduction We studied the distribution and in vitro pathogenicity of anti-DSG3 IgG subclasses during the course of pemphigus vulgaris (PV). Methods We longitudinally studied the distribution of anti-DSG3 IgG subclasses (before versus after treatment) in… read more here.

Keywords: anti dsg3; dsg3 igg; igg subclasses; sera ... See more keywords
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Dsg1 and Dsg3 Composition of Desmosomes Across Human Epidermis and Alterations in Pemphigus Vulgaris Patient Skin

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.884241

Abstract: Desmosomes are important epidermal adhesion units and signalling hubs, which play an important role in pemphigus pathogenesis. Different expression patterns of the pemphigus autoantigens desmoglein (Dsg)1 and Dsg3 across different epidermal layers have been demonstrated.… read more here.

Keywords: patient skin; composition; dsg3; dsg1 dsg3 ... See more keywords

Desmoglein compensation hypothesis fidelity assessment in Pemphigus

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.969278

Abstract: The pemphigus group of autoimmune blistering diseases encompasses pemphigus vulgaris (PV) and pemphigus foliaceus (PF). Lesion location in pemphigus has been elegantly postulated by the Desmoglein Compensation Hypothesis (DCH), which references the distribution of desmoglein… read more here.

Keywords: hypothesis; pemphigus; compensation hypothesis; dsg3 ... See more keywords
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Detection of rare autoreactive T cell subsets in patients with pemphigus vulgaris

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.979277

Abstract: Analysis of T lymphocyte proliferation and activation after antigenic or mitogenic stimulation is a vital parameter used in the diagnosis of various immuno-deficiencies and during the monitoring of treatment responses. Most applied techniques are based… read more here.

Keywords: cell; pemphigus vulgaris; cd4 cells; cd4 ... See more keywords
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A Novel In Vivo Active Pemphigus Model Targeting Desmoglein1 and Desmoglein3: A Tool Representing All Pemphigus Variants

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Published in 2023 at "Biology"

DOI: 10.3390/biology12050702

Abstract: Simple Summary Pemphigus is a severe and heterogeneous autoimmune disease determining the formation of blisters in the skin and mucosae. Life quality of patients is indeed deteriorated by the disease. The different kinds of pemphigus… read more here.

Keywords: dsg1 dsg3; disease; pemphigus; dsg3 ... See more keywords