Articles with "dtag system" as a keyword



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The dTAG system for immediate and target-specific protein degradation

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Published in 2018 at "Nature Chemical Biology"

DOI: 10.1038/s41589-018-0021-8

Abstract: Dissection of complex biological systems requires target-specific control of the function or abundance of proteins. Genetic perturbations are limited by off-target effects, multicomponent complexity, and irreversibility. Most limiting is the requisite delay between modulation to… read more here.

Keywords: degradation; target specific; target; dtag system ... See more keywords