Dr. Jekyll and Mr. Hyde: Oxidizable phenol‐generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation
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DOI: 10.1016/j.freeradbiomed.2018.06.039
Abstract: Abstract The transcription factor Nrf2 is a master regulator of antioxidant and cytoprotective genes, binding to antioxidant response elements (AREs) in their promoter regions. Due to the therapeutic role of the Nrf2/ARE system in oxidative… read more here.
Keywords: accumulation; nrf2 protein; dtbhq; expression ... See more keywords