Cost-Utility Analysis of a Dolutegravir-Based Versus Low-Dose Efavirenz-Based Regimen for the Initial Treatment of HIV-Infected Patients in Cameroon (NAMSAL ANRS 12313 Trial)
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DOI: 10.1007/s40273-020-00987-3
Abstract: Evidence comparing the economic and patient values of the World Health Organization’s preferred (dolutegravir 50 mg [DTG]-based) and alternative (low-dose [400 mg] efavirenz [EFV400]-based) first-line antiretroviral regimens is limited. We compared patient-reported outcomes (PROs), costs,… read more here.
Keywords: trial; dtg based; utility; analysis ... See more keywords
Viral suppression in the era of transition to dolutegravir-based therapy in Cameroon: Children at high risk of virological failure due to the lowly transition in pediatrics
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DOI: 10.1097/md.0000000000033737
Abstract: This study aimed to compare viral suppression (VS) between children, adolescents, and adults in the frame of transition to dolutegravir (DTG)-based antiretroviral therapy (ART) in the Cameroonian context. A comparative cross-sectional study was conducted from… read more here.
Keywords: dtg based; therapy; viral suppression; transition dolutegravir ... See more keywords
Challenges of scale-up to Dolutegravir based regimens in sub-Saharan Africa: a case study in Togo.
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DOI: 10.1097/qad.0000000000002470
Abstract: OBJECTIVE Evaluate the potential effectiveness of the implementation of DTG-based regimens in patients on failing current ART given the high levels of NRTI resistance in Togo. DESIGN Patients on ART attending health facilities for routine… read more here.
Keywords: saharan africa; dtg based; based regimens; togo ... See more keywords
Cohort profile: The Observational cohort for the study of DOlutegravir in Antiretroviral Combination REgimens (ODOACRE)
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DOI: 10.1136/bmjopen-2019-029960
Abstract: Purpose The Observational cohort for the study of DOlutegravir in Antiretroviral Combination REgimens (ODOACRE) cohort was established in Italy in 2016 to evaluate the overall efficacy and tolerability of dolutegravir (DTG)-based antiretroviral (ARV) regimens in… read more here.
Keywords: dtg based; odoacre cohort; cohort; observational cohort ... See more keywords
Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting
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DOI: 10.1155/2024/4620951
Abstract: Background: Following the 2018 World Health Organization's (WHO) guidelines on HIV treatment and management, the Zimbabwean government has embraced dolutegravir (DTG)-based regimens as the preferred first-line treatment for people living with HIV (PLWH). Despite this… read more here.
Keywords: lipid levels; people living; dtg based; body weight ... See more keywords
The safety of a dolutegravir (DTG)-based antiretroviral treatment (ART) regimen for pregnancy and birth outcomes in Ethiopia: evidence from multicenter cohort study
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DOI: 10.1186/s12879-024-09763-6
Abstract: A dolutegravir (DTG)-based antiretroviral regimen has been rolled out for pregnant women in low- and middle-income countries since 2020. However, available safety data are limited to a few clinical trials and observational studies. Hence, we… read more here.
Keywords: pregnancy birth; birth; pregnancy; dtg based ... See more keywords
Impact of scaling up dolutegravir on antiretroviral resistance in South Africa: A modeling study
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DOI: 10.1371/journal.pmed.1003397
Abstract: Background Rising resistance of HIV-1 to non-nucleoside reverse transcriptase inhibitors (NNRTIs) threatens the success of the global scale-up of antiretroviral therapy (ART). The switch to WHO-recommended dolutegravir (DTG)-based regimens could reduce this threat due to… read more here.
Keywords: based art; south africa; dtg based; dtg ... See more keywords
A Phase-IV Non-interventional Study to Assess Virological Effectiveness, Safety, and Tolerability of DTG-based Antiretroviral Therapy in HIV-1 Infected Indian Persons Living with HIV.
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DOI: 10.2174/011570162x264021231108010324
Abstract: BACKGROUND Dolutegravir (DTG) is a novel yet preferential first-and-second-line treatment for persons living with HIV (PLH). Owing to its recent introduction, DTG-based regimens have not undergone a comprehensive, systematic evaluation regarding their real-world utilization and… read more here.
Keywords: hiv; persons living; dtg based; dtg ... See more keywords