Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes
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DOI: 10.1038/s41467-019-13719-9
Abstract: While Tn-Seq is a powerful tool to determine genome-wide bacterial fitness in high-throughput, culturing transposon-mutant libraries in pools can mask community or other complex single-cell phenotypes. Droplet Tn-Seq (dTn-Seq) solves this problem by microfluidics facilitated… read more here.
Keywords: single cell; complex single; cell phenotypes; droplet seq ... See more keywords