Abstract 425: Characterization of TKI-induced drug-tolerant persister cells from a patient-derived cell line
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-425
Abstract: Introduction: Targeted therapies provide clinical benefits in patients harboring oncogene-driven cancers, but relapses invariably occur. Studies on resistance mechanisms are essential to guide the development of next-generation inhibitors. An increasing number of studies focus on… read more here.
Keywords: cell; tolerant; dtp cells; drug ... See more keywords
GDF15 Is an Eribulin Response Biomarker also Required for Survival of DTP Breast Cancer Cells
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DOI: 10.3390/cancers14102562
Abstract: Simple Summary Drug tolerant persister (DTP) cells are a unique, small sub-population of cancer cells that maintain viability under anti-cancer cytotoxic treatments. These cells enter into a reversible drug-tolerant state, which is believed to be… read more here.
Keywords: breast cancer; dtp cells; gdf15; biomarker ... See more keywords