Ethyl acetate fraction from methanol extraction of Vitis thunbergii var. taiwaniana induced G0/G1 phase arrest via inhibition of cyclins D and E and induction of apoptosis through caspase‐dependent and ‐independent pathways in human prostate carcinoma DU145 cells
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Toxicology"
DOI: 10.1002/tox.22491
Abstract: Vitis thunbergii var. taiwaniana (VTT) is a wild grape native to Taiwan, belonging to the Vitaceae family and Vitis genus, and widely used as folk herbal medicine. It is traditionally used for the treatment of… read more here.
Keywords: human prostate; apoptosis; du145 cells; du145 ... See more keywords
CCL2 induces resistance to the antiproliferative effect of cabazitaxel in prostate cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Science"
DOI: 10.1111/cas.13876
Abstract: Understanding the mechanism of chemoresistance and disease progression in patients with prostate cancer is important for developing novel treatment strategies. In particular, developing resistance to cabazitaxel is a major challenge in patients with docetaxel‐resistant and… read more here.
Keywords: du145 txr; cabazitaxel; prostate cancer; du145 ... See more keywords
Abstract 1095: Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) regulates mitochondrial dynamics, EMT and angiogenesis in progression of prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-1095
Abstract: Prostate cancer (PCa) is a major epithelial cancer among men and with the second highest incidence rate, worldwide. The high ratio of IGF-1/IGFBP-3 correlates with increased risk of many cancers including prostate cancer. In present… read more here.
Keywords: igfbp; prostate cancer; du145; cancer ... See more keywords
FAM84B promotes prostate tumorigenesis through a network alteration
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DOI: 10.1177/1758835919846372
Abstract: Background: The aim of this study was to investigate the contributions of FAM84B in prostate tumorigenesis and progression. Methods: A FAM84B mutant with deletion of its HRASLS domain (ΔHRASLS) was constructed. DU145 prostate cancer (PC)… read more here.
Keywords: prostate tumorigenesis; hrasls; network; fam84b ... See more keywords
Cytostatic Effects of Methanolic Extracts of Amsonia orientalis Decne. on MCF-7 and DU145 Cancer Cell Lines
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DOI: 10.15835/nbha45110576
Abstract: Amsonia orientalis is an ornamental plant with anti-cancer properties. To characterize the anti-cancer potential of the species, methanolic extracts were prepared from leaf and stem tissues of field-grown individuals. Also, a mixture of stems, leaves… read more here.
Keywords: methanolic extracts; du145; mcf; cancer cell ... See more keywords
Aba enhances the apoptotic effect of docetaxel in the multidrug-resistant DU145 prostate cancer cell line
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DOI: 10.2298/abs240812031s
Abstract: This study aimed to induce drug resistance in DU145 prostate cancer cells by exposing them to docetaxel and mitoxantrone, and to examine the effects of combining docetaxel and abscisic acid (ABA). The IC50 values for… read more here.
Keywords: prostate cancer; aba; du145; docetaxel ... See more keywords
The Role of Curcumin in Prostate Cancer Cells and Derived Spheroids
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DOI: 10.3390/cancers14143348
Abstract: Simple Summary In recent years, considerable efforts have been made to discover new compounds useful for prostate cancer (PC) therapy and related clinical management. Promising advances in this field were reached with nutraceutical compounds. Curcumin… read more here.
Keywords: prostate cancer; curcumin; chemotherapeutic agents; du145 ... See more keywords