Effect of boron compounds on the biological effectiveness of proton therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15824
Abstract: PURPOSE We assessed whether adding sodium borocaptate (BSH) or 4-borono-L-phenylalanine (BPA) to cells irradiated with proton beams influenced the biological effectiveness of those beams against prostate cancer cells to investigate if the alpha particles generated… read more here.
Keywords: du145 cells; biological effectiveness; effectiveness proton; h2ax 53bp1 ... See more keywords
Moracin D induces apoptosis in prostate cancer cells via activation of PPAR gamma/PKC delta and inhibition of PKC alpha
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7313
Abstract: Herein, apoptotic mechanism of Moracin D was explored in prostate cancer cells in association with peroxisome proliferator‐activated receptor gamma (PPAR‐γ)‐related signaling involved in lipid metabolism. Moracin D augmented cytotoxicity and sub G1 population in PC3… read more here.
Keywords: cancer cells; pkc; moracin; du145 cells ... See more keywords
Ethyl acetate fraction from methanol extraction of Vitis thunbergii var. taiwaniana induced G0/G1 phase arrest via inhibition of cyclins D and E and induction of apoptosis through caspase‐dependent and ‐independent pathways in human prostate carcinoma DU145 cells
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Toxicology"
DOI: 10.1002/tox.22491
Abstract: Vitis thunbergii var. taiwaniana (VTT) is a wild grape native to Taiwan, belonging to the Vitaceae family and Vitis genus, and widely used as folk herbal medicine. It is traditionally used for the treatment of… read more here.
Keywords: human prostate; apoptosis; du145 cells; du145 ... See more keywords
Procyanidin from peanut skin induces antiproliferative effect in human prostate carcinoma cells DU145.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.04.008
Abstract: In this study, the antiproliferative activity of peanut skin procyanidins (PSP) and six fractions (PSP-1∼6) isolated from PSP by several chromatographic steps on the human prostate cancer DU145 cells were evaluated. The results showed that PSP… read more here.
Keywords: prostate; procyanidin peanut; human prostate; du145 cells ... See more keywords
Protective effect of procyanidin A-type dimers against H2O2-induced oxidative stress in prostate DU145 cells through the MAPKs signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118908
Abstract: It has been reported that B-type procyanidins can alleviate oxidative damage of prostatic cells, but there has been limited information on the similar role of A-type procyanidins. This study investigated the protective effect of procyanidin… read more here.
Keywords: procyanidin type; du145 cells; type dimers; h2o2 induced ... See more keywords
Flavonoid brachydin B decreases viability, proliferation, and migration in human metastatic prostate (DU145) cells grown in 2D and 3D culture models.
Sign Up to like & getrecommendations! Published in 2023 at "Toxicology research"
DOI: 10.1093/toxres/tfad019
Abstract: Brachydin B (BrB) is a unique dimeric flavonoid extracted from Fridericia platyphylla (Cham.) LG Lohmann with different biological activities. However, the antitumoral potential of this flavonoid is unclear. In our study, we evaluated the effects… read more here.
Keywords: prostate du145; du145 cells; migration; metastatic prostate ... See more keywords