Transition metal-free carboxylation of terminal alkynes with carbon dioxide through dual activation: Synthesis of propiolic acids
Sign Up to like & getrecommendations! Published in 2019 at "Journal of CO2 Utilization"
DOI: 10.1016/j.jcou.2019.04.011
Abstract: Abstract The combination use of quaternary ammonium salt and inorganic base in low-boiling-point solvent is presented as a new strategy for terminal alkyne carboxylation with CO2. The carboxylation of terminal alkyne with CO2 proceeded smoothly… read more here.
Keywords: transition metal; dual activation; carboxylation; carboxylation terminal ... See more keywords
Asymmetric epoxidation of α,β-unsaturated ketones via an amine-thiourea dual activation catalysis
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.152941
Abstract: Abstract A simple asymmetric epoxidation method is developed to effectively synthesize chiral α-carbonyl epoxides through an amine-thiourea dual activation catalysis. In this method, TBHP, as an oxidant, determined the reaction rate, and the chiral amine-thiourea… read more here.
Keywords: thiourea dual; activation catalysis; unsaturated ketones; dual activation ... See more keywords
Cu(II)-Catalyzed, Site Selective Sulfoximination to Indole and Indolines via Dual C-H/N-H Activation.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02817
Abstract: A copper-catalyzed protocol furnishing N-arylated sulfoximines has been developed via dual N-H/C-H activation. Arylalkyl- and less reactive diarylsulfoximines were efficiently coupled with privileged scaffolds like indolines, indoles, and N-Ar-7-azaindoles. Sulfoximines based on medicinally relevant scaffolds… read more here.
Keywords: selective sulfoximination; dual activation; site selective; catalyzed site ... See more keywords
Dual Activation Strategy to Achieve C-C Cleavage of Cyclobutanes: Development and Mechanism of Rh and Zn Cocatalyzed [4 + 2] Cycloaddition of Yne-Vinylcyclobutanones.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c04244
Abstract: Reported here is the Rh and Zn cocatalyzed [4 + 2] cycloaddition of newly designed yne-vinylcyclobutanones, which can generate 5/6 or 6/6 bicyclic products with an all-carbon quaternary bridgehead center. The reaction has a broad… read more here.
Keywords: cocatalyzed cycloaddition; yne vinylcyclobutanones; cleavage; dual activation ... See more keywords
A novel near-infrared theranostic probe for accurate cancer chemotherapy in vivo by a dual activation strategy.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc05864a
Abstract: A novel theranostic probe called CX-B-DF is constructed for precise chemotherapy guided by near-infrared (NIR) fluorescence imaging. Moreover, the theranostic probe shows high cytotoxicity to cancer cells under dual activation (H2O2 and TP), which causes… read more here.
Keywords: cancer; probe; chemotherapy; theranostic probe ... See more keywords
Epigenetic Programming Effects of Early Life Stress: A Dual-Activation Hypothesis
Sign Up to like & getrecommendations! Published in 2018 at "Current Genomics"
DOI: 10.2174/1389202919666180307151358
Abstract: Epigenetic processes during early brain development can function as ‘developmental switches’ that contribute to the stability of long-term effects of early environmental influences by programming central feedback mechanisms of the HPA axis and other neural… read more here.
Keywords: programming; dual activation; effects early; stress ... See more keywords