Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
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DOI: 10.1039/d2ra06019a
Abstract: Therapy resistance remains a challenge for the clinics. Here, dual-active chemicals that simultaneously inhibit independent functions in disease-relevant proteins are desired though highly challenging. As a model, we here addressed the unique protease threonine aspartase… read more here.
Keywords: threonine; dual activity; bisphosphate; threonine aspartase ... See more keywords