A dual-adjuvant neoantigen nanovaccine loaded with imiquimod and magnesium enhances anti-tumor immune responses of melanoma.
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DOI: 10.1039/d2bm01340a
Abstract: Neoantigen-based tumor vaccines have been applied in patient-specific melanoma-derived immunogenic mutated epitopes (neoantigens), with potential antineoplastic and immunomodulating effects. Yet, their use is limited by different physicochemical properties and poor pharmacokinetics. Herein, we constructed a… read more here.
Keywords: magnesium; dual adjuvant; neoantigen nanovaccine; tumor ... See more keywords