Dual amplification of a bio-barcode and auto-cycling primer extension for highly sensitive detection of miRNA.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03864a
Abstract: MicroRNAs (miRNAs) can be used as biomarkers for the diagnosis and therapy of cancers. However, their low abundance and the complex environment in biological samples hinder miRNA detection. A dual amplification strategy based on the… read more here.
Keywords: cycling primer; auto cycling; amplification; detection ... See more keywords
Dual amplification strategy turns TRPM2 channels into supersensitive central heat detectors
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212378119
Abstract: Significance Thermoregulation in the mammalian body is mediated by a central brain thermostat. Because deep-brain temperatures are maintained within a narrow range, the thermostat must contain a sensor that can differentiate temperature fluctuations as small… read more here.
Keywords: strategy turns; amplification strategy; channels supersensitive; dual amplification ... See more keywords