Ingestion-time differences in the pharmacodynamics of dual-combination hypertension therapies: Systematic review and meta-analysis of published human trials.
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DOI: 10.1080/07420528.2021.2005084
Abstract: The pharmacodynamics of hypertension medications can be significantly affected by circadian rhythms in the biological mechanisms of the 24 h blood pressure (BP) pattern. Hypertension guidelines fail to recommend the time of day when patients, including… read more here.
Keywords: time; dual combination; ingestion time; pathology ... See more keywords
Real-world comparison of mono and dual combination therapies of metformin, sulfonylurea, and dipeptidyl peptidase-4 inhibitors using a common data model
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DOI: 10.1097/md.0000000000028823
Abstract: Abstract The comparative effectiveness of oral hypoglycemic agents on glycemic control and chronic complications in clinical practice is unknown in Korea. This study aimed to compare glycemic control and the incidence of hypoglycemia and chronic… read more here.
Keywords: peptidase inhibitors; dipeptidyl peptidase; chronic complications; dual combination ... See more keywords