Design, synthesis, and biological evaluation of novel dual FFA1 (GPR40)/PPARδ agonists as potential anti-diabetic agents.
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DOI: 10.1016/j.bioorg.2019.103254
Abstract: The free fatty acid receptor 1 (FFA1) and peroxisome proliferator-activated receptor δ (PPARδ) were considered as potential anti-diabetic targets, and the dual FFA1/PPARδ agonists might provide synergistic effect in insulin secretion and sensibility. Herein, we… read more here.
Keywords: ppar; ppar agonists; ffa1; potential anti ... See more keywords